Results 51 to 60 of about 162,145 (289)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

What matters when? – An integrative literature review on decision criteria in different stages of the adaptive reuse process

Developments in the Built Environment
Despite the significant growth of the literature on adaptive reuse, little is known about the specific criteria unfolding throughout the different phases of the adaptive reuse decision-making process.
Brian van Laar, Angela Greco, Hilde Remøy, Vincent Gruis   +3 more
doaj   +1 more source

Revitalizing Cities: Adaptive Reuse of Historic Structures [PDF]

, 2012
Adaptive reuse is employed when revitalizing an existing infrastructure while maintaining important aspects of the cultural architectural heritage and promoting sustainability.
Sharpe, Sara E
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Assessing the environmental benefits of adaptive reuse in historical buildings. A case study of a life cycle assessment approach

Sustainable Environment
This investigation delineates the environmental ramifications of the adaptive reuse of historic buildings through a comprehensive life cycle analysis (LCA) posed against traditional demolition and construction approaches.
Ming Hu, Jakub Świerzawski
doaj   +1 more source

Adaptive just-in-time code diversification [PDF]

, 2015
We present a method to regenerate diversified code dynamically in a Java bytecode JIT compiler, and to update the diversification frequently during the execution of the program.
Blazakis D., Giuffrida C., Niu B., Wei T.   +3 more
core   +3 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

LIGHT IN COMMUNITY: a study in the adaptive reuse of sacred space [PDF]

, 2019
MOTIVATION American life is increasingly fragmented, leading to a sense of restlessness and disconnection. Much of that fragmentation can be traced to our pattern of architectural and sociological development, namely, the rise of the automobile suburbs ...
Barras, Abigail
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Adaptive reuse of industrial buildings for housing using ARP and AdaptSTAR models

City and Environment Interactions
The man-made environment significantly impacts human living conditions and building design, particularly in housing, by creating economic, psychosocial, policy, and environmental challenges.
Sara Tavakoli, Seyed Abbas Yazdanfar, Neda Sadat Sahragard Monfared   +2 more
doaj   +1 more source