Results 41 to 50 of about 15,337 (259)
Adaptive re-use gives new cycle to a site, instead of freezing it at a particular moment in time, it explores the options of destruction to recreation. Planting a new layer without erasing the roots of earlier layers, an adaptive reuse continues with its identity of long history, along with addressing the concerns to scarcity of land.
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Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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This investigation delineates the environmental ramifications of the adaptive reuse of historic buildings through a comprehensive life cycle analysis (LCA) posed against traditional demolition and construction approaches.
Ming Hu, Jakub Świerzawski
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Sustainable development has become a goal for all countries seeking a balance between social, environmental and economic needs. The principal vision of a sustainable built future is about developing creative designs that utilize energy and materials ...
Othman Ayman Ahmed Ezzat, Elsaay Heba
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Adaptive reuse potential [PDF]
PurposeAdaptive reuse of existing building stock that has reached the end of its useful life, but not its physical life, is an important ingredient in the necessary adaptation of the constructed environment due to the impact of climate change and the need to conserve valuable resources into the future.
Shen, Li-yin, Langston, Craig
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Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
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In the decision-making process for investing in heritage buildings (HBs), various factors such as costs, interests, and tenancy terms influence investors decisions. Understanding the motivations of these investors can facilitate the involvement of social
Kailun Fang, Yifei Wu
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
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This study proposes a model that supports designers’ decision-making in the adaptive reuse process of existing buildings. The model, called “RE-USE MAP,” aims to extract data from the existing building through its generated Revit model (such as ...
Ömer Ruhlukürkçü +1 more
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
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