Results 31 to 40 of about 15,337 (259)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Adaptive Property Reuse for Social Housing: Benefits, Challenges, and Best Practices

Baltic Journal of Real Estate Economics and Construction Management
This study examines the adaptive reuse of properties for the development of social housing, focusing on the benefits, challenges, and best practices associated with this approach.
Sanchaniya Rashmi Jaymin, Černeckienė Jurgita, Gudumasu Naga Shilpa, Kundziņa Antra   +3 more
doaj   +1 more source

The Criteria For Decision Making In Adaptive Reuse Towards Sustainable Development

MATEC Web of Conferences, 2016
Adaptive reuse is an important strategy for achieving sustainability as it ensures a continuous building life cycle and prevents building destruction.
Mohamed Noorzalifah, Alauddin Kartina
doaj   +1 more source

The Boyen Fortress: structural analysis of selecting complementary forms of use for a proposed adaptive reuse project

Heritage Science, 2021
Extending the life cycle of heritage buildings through their adaptive reuse can ensure their survival and is concordant with the policy of sustainable development.
Grzegorz Śladowski, Bartłomiej Szewczyk, Krzysztof Barnaś, Olga Kania, Janusz Barnaś   +4 more
doaj   +1 more source

A Dual Strategy in the Adaptive Reuse of Industrial Heritage Buildings: The Shanghai West Bund Waterfront Refurbishment

Buildings, 2023
Waterfront intervention, as one of the post-industrial reuse paradigms, has flourished around the world and been studied as a global phenomenon. This paper investigates the application of a dual adaptive reuse strategy to industrial heritage waterfront ...
Pengfei Ma, Xiangning Li, Di Lan
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A fuzzy approach for adaptive reuse selection of industrial buildings in Hong Kong

International Journal of Strategic Property Management, 2014
With rapid economic development and restructuring, there are an increasing number of aged or obsolete buildings in large cities, such as Hong Kong.
Yongtao Tan, Li-yin Shen, Craig Langston
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

What matters when? – An integrative literature review on decision criteria in different stages of the adaptive reuse process

Developments in the Built Environment
Despite the significant growth of the literature on adaptive reuse, little is known about the specific criteria unfolding throughout the different phases of the adaptive reuse decision-making process.
Brian van Laar, Angela Greco, Hilde Remøy, Vincent Gruis   +3 more
doaj   +1 more source