Results 31 to 40 of about 22,359 (301)
Humaniora, 2023 The research examined the adaptive reuse strategy of heritage buildings that hold nostalgic value as commercial spaces with the third-place concept approach. The need for space facilities for urban communities continued to change based on the activities
Ade Ariyani Sari Fajarwati
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
S Sustainable Viability for Restoration and Adaptive Reuse of Sikh Era Havelis in Lahore, Pakistan
Sir Syed University Research Journal of Engineering and Technology, 2020 This research is concept based investigation of assessing the practical viability in terms of sustainability, for restoration and adaptive reuse of Sikh Era historic Havelis in Lahore.
Dr Sadia Farooq, Amna Khalid Qureshi
doaj
Adaptive Heritage Reuse: Mapping Policies and Regulations
, 2023 Adaptive heritage reuse (AHR) has seen a flourishing of interest in the last decade within the European context of this study, both as a practice, and in scholarly work.
Dóra Mérai +2 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Criteria For Decision Making In Adaptive Reuse Towards Sustainable Development
MATEC Web of Conferences, 2016 Adaptive reuse is an important strategy for achieving sustainability as it ensures a continuous building life cycle and prevents building destruction.
Mohamed Noorzalifah, Alauddin Kartina
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Heritage Science, 2021 Extending the life cycle of heritage buildings through their adaptive reuse can ensure their survival and is concordant with the policy of sustainable development.
Grzegorz Śladowski +4 more
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Buildings, 2023 Waterfront intervention, as one of the post-industrial reuse paradigms, has flourished around the world and been studied as a global phenomenon. This paper investigates the application of a dual adaptive reuse strategy to industrial heritage waterfront ...
Pengfei Ma, Xiangning Li, Di Lan
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source