Results 51 to 60 of about 15,337 (259)

Evaluating the Contributions of Adaptive Reuse to Urban Design

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA
This study aims to examine the integration of a reused building with the city. To this aim, this study evaluates adaptive reuse ideas in a chosen historical building, Şehbenderler Mansion Library, in İbrahimpaşa Neighborhood, Bursa.
Saliha Aslan, Alper Gönül
doaj   +1 more source

Reusing Adaptation Strategies in Adaptive Educational Hypermedia Systems [PDF]

2010 10th IEEE International Conference on Advanced Learning Technologies, 2010
Due to the difficulty and thus effort and expenses involved in creating them, personalization strategies in learning environments have to demonstrate a higher return-on-investment (ROI), if they are to be a viable component of the learning setting of the future.
Joshua Scotton, Alexandra I. Cristea
openaire   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Adaptive reuse of industrial buildings for housing using ARP and AdaptSTAR models

City and Environment Interactions
The man-made environment significantly impacts human living conditions and building design, particularly in housing, by creating economic, psychosocial, policy, and environmental challenges.
Sara Tavakoli, Seyed Abbas Yazdanfar, Neda Sadat Sahragard Monfared   +2 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Post-Adaptive Reuse Evaluation of Heritage Spaces: A Case Study of Dar Al Saraya in Madaba, Jordan

Architecture
Adaptive reuse of heritage buildings is a vital strategy for balancing cultural preservation with modern functionality needs. This study provides a post-adaptive reuse evaluation of Dar Al Saraya in Madaba, Jordan, a significant Ottoman-era landmark, to ...
Dana Khalid Amro, Malak Abu Nasser
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Assessment of Adaptive Reuse of Heritage Shop Houses for Sleep Lodging in Malaysia: Fulfilment of Conservation Guidelines

SHS Web of Conferences, 2014
This study focuses on the compliance of adaptive reuse of historic shop houses for sleep lodging with reference to the Guidelines for Conservation Areas and Heritage Buildings by Majlis Perbandaran Pulau Pinang (MPPP).
Othuman Mydin M.A., Keling N.A., Sani N. Md., Abas N.F   +3 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source