Results 71 to 80 of about 110,015 (262)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Adaptive optimisation of the management of Korean pine plantation
Forest EcosystemsForest management planning faces uncertainties regarding future timber prices, tree growth, and survival. Future seed production is an additional source of uncertainty in Korean pine stands managed for the joint production of timber and edible seeds ...
Qianping Tong +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Inversion of the Laplace Transform from the Real Axis Using an Adaptive Iterative Method
International Journal of Mathematics and Mathematical Sciences, 2009 A new method for inverting the Laplace transform from the real axis is formulated. This method is based on a quadrature formula. We assume that the unknown function 𝑓(𝑡) is continuous with (known) compact support.
Sapto W. Indratno, Alexander G. Ramm
doaj +1 more source
Evaluation of an adaptive, rule-based dosing algorithm to maintain therapeutic anticoagulation during atrial fibrillation ablation. [PDF]
Cardiovasc Digit Health J, 2023 Kalscheur MM +8 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
International Journal of Antennas and Propagation, 2018 Degree of freedom (DOF) of clutter in the reduced-dimension (RD) domain, which is called local DOF (LDOF), is of great importance for RD MIMO-STAP (space-time adaptive processing for multiple-input multiple-output radar) algorithms.
Yiduo Guo, Jian Gong, Yu Xiao
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Research and Application of an Improved Sparrow Search Algorithm
Applied SciencesAssociation rule mining utilizing metaheuristic algorithms is a prominent area of study in the field of data mining. However, when working with extensive data, conventional metaheuristic algorithms exhibit limited search efficiency and face challenges in
Liwei Hu, Denghui Wang
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source