Results 71 to 80 of about 5,787,644 (326)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Fractional order adaptive MRAC controller for an active suspension system
Algerian Journal of Signals and Systems, 2020 This paper investigates the use of fractional order operators in conventional model reference adaptive control (MRAC). A fractional adaptive controller is designed based on the use of a fractional-order parameter adjustment rule.
SEIF EDDINE KHELAS +2 more
doaj +1 more source
A machine learning approach with verification of predictions and assisted supervision for a rule-based network intrusion detection system [PDF]
, 2008 Network security is a branch of network management in which network intrusion detection systems provide attack detection features by monitorization of traffic data.
Fernández Villamor, José Ignacio +1 more
core +1 more source
QuickSync: A Quickly Synchronizing PoS-Based Blockchain Protocol
, 2021 To implement a blockchain, we need a blockchain protocol for all the nodes to follow. To design a blockchain protocol, we need a block publisher selection mechanism and a chain selection rule.
Gujar, Sujit, Siddiqui, Shoeb
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Adaptive Rule-Base Influence Function Mechanism for Cultural Algorithm [PDF]
Journal of Advances in Computer Engineering and Technology, 2015 This study proposes a modified version of cultural algorithms (CAs) which benefits from rule-based system for influence function. This rule-based system selects and applies the suitable knowledge source according to the distribution of the solutions ...
Vahid Seydi Ghomsheh +2 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source