Results 101 to 110 of about 3,594,430 (292)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Journal of Marine Science and EngineeringSubmesoscale processes, characterized by strong vertical velocities that generate sea surface temperature (SST) fronts as well as O(1) Rossby number (Ro), are critical to ocean mixing and biogeochemical transport, yet their observation is hampered by ...
Wenbo Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Theoretically Grounded Adaptive Sampling for Imbalanced Multi-Label Classification in Medical Text
IEEE AccessMulti-label medical text classification faces severe class imbalance, where rare pathological conditions appear hundreds of times less frequently than common findings.
Kyung Won Cho +2 more
doaj +1 more source
Halton Sampling for Image Registration Based on Mutual Information
, 2008 Mutual information is a widely used similarity measure for aligning multimodal medical images. At its core, it relies on the computation of a discrete joint histogram, which itself requires image samples for its estimation.
Michel Bierlaire +5 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Reviews of the Static, Adoptive, and Dynamic Sampling in Wafer Manufacturing
Applied System InnovationSemiconductor wafer manufacturing is one of the most complex and data-intensive processes in the industry, encompassing the front-end (FEOL), middle-end (MOL), and back-end (BEOL) stages, involving thousands of interdependent processes.
Hsuan-Yu Chen, Chiachung Chen
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
MathematicsTwo key challenges in financial distress prediction are pronounced class imbalance between majority and minority classes and the persistent misclassification of hard-to-learn samples.
Guodong Hou +3 more
doaj +1 more source
An Efficient Scheme for Broadband Adaptive Beamforming [PDF]
, 1999 This paper introduces an oversampled subband approach to linearly constrained minimum variance adaptive broadband beamforming. This method is motivated by the considerable reduction in computation over fullband implementation and resulting large ...
S. Weiss +18 more
core +1 more source