Results 91 to 100 of about 260,991 (264)

Enhanced Detection of Mitochondrial Heteroplasmy and DNA Hypomethylation in Adipose-Derived Mesenchymal Stem Cells Using a Novel Adaptive Sampling Protocol

Applied Sciences
Objective: Mitochondria drive cellular energy production and regulate key biological processes. High levels of heteroplasmic in mitochondrial DNA (mtDNA) variants can cause mitochondrial dysfunction and clinical symptoms.
Antonina Gospodinova, Yuliia Mariienko, Diana Pendicheva-Duhlenska, Soren Hayrabedyan, Krassimira Todorova   +4 more
doaj   +1 more source

Adaptive visual sampling

, 2010
PhDVarious visual tasks may be analysed in the context of sampling from the visual field. In visual psychophysics, human visual sampling strategies have often been shown at a high-level to be driven by various information and resource related factors ...
Raja, Yogesh
core  

A Subband Adaptive Equalization Structure

, 1999
The potential presence of fractional delays, non-minimum phase parts, and a colouring of the channel output can require adaptive equalizers to adapt very long impulse responses.
Weiss, Stephan, S. Weiss, Weiss, S, Garcia-Alis, D, Garcia-Alis, Daniel, Stewart, R W, Stewart, Robert   +6 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Aero-Structural Design Optimization of a Transonic Fan Rotor Using an Adaptive POD-Based Hybrid Surrogate Model

Aerospace
In this study, an optimization framework for turbomachinery blades using a hybrid surrogate model assisted by proper orthogonal decomposition (POD) is introduced and then applied to the aero-structural multidisciplinary design optimization of a transonic
Jiaqi Luo, Zhen Fu, Jiaxing Li
doaj   +1 more source

Effectiveness of Adaptive Window Scans in Reducing Near-Field Measurement Time [PDF]

Journal of Electromagnetic Engineering and Science
The widespread application of near-field scanning is limited by its long measurement time. This article proposes a window-scanning-based automated adaptive sampling approach to address this issue.
Hakim Azizi, Mohammed Chebout, Mohammed Charif Kihal, Daoud Sekki, Marouane Kihal, Hocine Moulai   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Adaptive Gibbs samplers and related MCMC methods [PDF]

, 2011
We consider various versions of adaptive Gibbs and Metropolis- within-Gibbs samplers, which update their selection probabilities (and perhaps also their proposal distributions) on the y during a run, by learning as they go in an attempt to optimise ...
Rosenthal, Jeffrey S. (Jeffrey Seth), Łatuszyński, Krzysztof, Roberts, Gareth O.   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Gibbs sampling, adaptive rejection sampling and robustness to prior specification for a mixed linear model [PDF]

, 1997
Markov chain Monte-Carlo methods are increasingly being applied to make inferences about the marginal posterior distributions of parameters in quantitative genetic models.
CM Theobald, Thompson, R., Thompson R, Firat M.Z., R. Thompson, Theobald, C. M., Firat, M. Z., Thompson R., MZ Firat, Firat MZ, Theobald CM, R Thompson, Theobald C.M.   +12 more
core   +1 more source