Results 91 to 100 of about 3,594,430 (292)
AerospaceIn this study, an optimization framework for turbomachinery blades using a hybrid surrogate model assisted by proper orthogonal decomposition (POD) is introduced and then applied to the aero-structural multidisciplinary design optimization of a transonic
Jiaqi Luo, Zhen Fu, Jiaxing Li
doaj +1 more source
Adaptive radial-based direction sampling; Some flexible and robust Monte Carlo integration methods [PDF]
Adaptive radial-based direction sampling (ARDS) algorithms are specified for Bayesian analysis of models with nonelliptical, possibly, multimodal target distributions.A key step is a radial-based transformation to directions and distances.
Dijk, H.K. van +3 more
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On adaptive sampling techniques for metamodels based on NURBS entities from unstructured data [PDF]
The paper investigates the influence of adaptive sampling strategies on the generation of a metamodel based on Non-Uniform Rational Basis Spline (NURBS) entities, obtained from unstructured data, with the purpose of improving accuracy while minimising ...
Zani, M. +5 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2023 Introduction Traditionally, the investigation of suspect food samples during an outbreak investigation requires the samples to be enriched in order to reach detectable levels.
T. Van Nieuwenhuysen +6 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Effectiveness of Adaptive Window Scans in Reducing Near-Field Measurement Time [PDF]
Journal of Electromagnetic Engineering and ScienceThe widespread application of near-field scanning is limited by its long measurement time. This article proposes a window-scanning-based automated adaptive sampling approach to address this issue.
Hakim Azizi +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
MathematicsPhysics-Informed Neural Networks (PINNs) represent a transformative approach to solving partial differential equation (PDE)-based boundary value problems by embedding physical laws into the learning process, addressing challenges such as non-physical ...
Sergiy Plankovskyy +5 more
doaj +1 more source
Explaining Adaptive Radial-Based Direction Sampling [PDF]
In this short paper we summarize the computational steps of Adaptive Radial-Based Direction Sampling (ARDS), which can be used for Bayesian analysis of ill behaved target densities.
Dijk, H.K. van +3 more
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