Results 81 to 90 of about 217,902 (307)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Applications of Adaptive Time Frequency Representations to Underwater Acoustic Signal Processing

open access: yes, 2006
Conference paperThe authors describe the application of an adaptive optimal kernel (AOK) time-frequency representation to the processing of underwater acoustic data. The optimal kernel is a signal-dependent radially Gaussian function.
Jones, Douglas L.   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A Single-Dataset-Based Pre-Processing Joint Domain Localized Algorithm for Clutter-Suppression in Shipborne High-Frequency Surface-Wave Radar

open access: yesSensors, 2020
Due to the motion of the platform, the spectrum of first-order sea clutter will widen and mask low-velocity targets such as ships in shipborne high-frequency surface-wave radar (HFSWR).
Liang Guo   +5 more
doaj   +1 more source

Adaptive simulated annealing for optimization in signal processing applications

open access: yes, 1999
Many signal processing applications pose optimization problems with multimodal and nonsmooth cost functions. Gradient methods are ineffective in these situations. The adaptive simulated annealing (ASA) offers a viable optimization tool for tackling these
Luk, B. L., Chen, S.
core  

Multicriteria Design of Oversampled Uniform DFT Filter Banks [PDF]

open access: yes, 2004
Subband adaptive filters have been proposed to avoid the drawbacks of slow convergence and high computational complexity associated with time domain adaptive filters.
Grbić, N   +11 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Efficient Subband Adaptive Filtering with Oversampled GDFT Filter Banks

open access: yes, 1997
This paper addresses the numerical efficiency of adaptive filtering implemented in subbands. Our approach first focuses on oversampled GDFT filter banks and their potential benefits over other possible subband decompositions.
Stephan Weiß   +8 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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