Results 61 to 70 of about 218,723 (262)

A novel sparse recovery space‐time adaptive processing algorithm using the log‐sum penalty to approximate the ℓ0 − norm penalty

IET Radar, Sonar & Navigation
Applying the sparse recovery (SR) technique to airborne radar space‐time adaptive processing (STAP) can greatly reduce the number of required training samples, which is advantageous in detecting targets in non‐homogeneous and non‐stationary clutter ...
Kun Liu, Tong Wang
doaj   +1 more source

A Single-Dataset-Based Pre-Processing Joint Domain Localized Algorithm for Clutter-Suppression in Shipborne High-Frequency Surface-Wave Radar

Sensors, 2020
Due to the motion of the platform, the spectrum of first-order sea clutter will widen and mask low-velocity targets such as ships in shipborne high-frequency surface-wave radar (HFSWR).
Liang Guo, Xin Zhang, Di Yao, Qiang Yang, Yang Bai, Weibo Deng   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Adaptive interference mitigation space‐time array reconfiguration by joint selection of antenna and delay tap

IET Radar, Sonar & Navigation
Space‐time adaptive processing (STAP) array has found extensive use in the global navigation satellite system for interference suppression. Nevertheless, the conventional space‐time array necessitates multiple antennas and time delay taps, resulting in a
Yandong Sun, Jian Xie, Yanyun Gong, Zhaolin Zhang, Ling Wang   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Adaptive Processing With Signal Contaminated Training Samples

IEEE Transactions on Signal Processing, 2013
We consider the adaptive beamforming or adaptive detection problem in the case of signal contaminated training samples, i.e., when the latter may contain a signal-like component. Since this results in a significant degradation of the signal to interference and noise ratio at the output of the adaptive filter, we investigate a scheme to jointly detect ...
Olivier Besson, Stéphanie Bidon
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source