Results 11 to 20 of about 250 (94)

Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives. [PDF]

Eur J Haematol
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gaidano G, Danesi R.
europepmc   +2 more sources

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, EarlyView.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

CHildren of the Cohort Study (CHOC): Exploring parenting desire among people living with HIV in Switzerland

HIV Medicine, EarlyView.
Abstract Background Although HIV is now a chronic condition with an excellent life expectancy, some personal aspects affecting people living with HIV (PLWH), such as parenting desire, are relatively understudied. This study aimed to explore parenting desire among PLWH in Switzerland.
Clara Merlin, José Damas, Olivier Nawej Tshikung, Noémie Wagner, Anna Hachfeld, Andrea Duppenthaler, Marcel Stoeckle, Malte Kohns, Irene A. Abela, Paolo Paioni, Luigia Elzi, Lisa Kottanattu, Patrick Schmid, Christian R. Kahlert, Katharina Kusejko, Pierre Alex Crisinel, Pascal Pellegrino, Matthias Cavassini, Katharine E. A. Darling, the Swiss HIV Cohort Study, IA Abela, K Aebi‐Popp, A Anagnostopoulos, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, JS Fehr, J Fellay, S Frigerio Malossa, CA Fux, HF Günthard, A Hachfeld, DHU Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, CR Kahlert, D Kaufmann, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, ND Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, Child Substudy, G Pantaleo, M Perreau, A Rauch, LP Salazar‐Vizcaya, P Schmid, O Segeral, RF Speck, M Stöckle, B Surial, PE Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +76 more
wiley   +1 more source

Earnings Trajectories Around Parenthood: Male Same‐Sex Couples in Denmark, the Netherlands and Sweden

Journal of Marriage and Family, EarlyView.
ABSTRACT Objective This study examines earnings trajectories of male same‐sex couples around the time they become parents in Denmark, the Netherlands, and Sweden: three forerunners in advancing same‐sex couples' legal rights but with different family policy frameworks.
Weverthon Machado, Marie Evertsson, Maaike van der Vleuten, Eva Jaspers   +3 more
wiley   +1 more source

Reference wet grasslands to support conservation and restoration assessments in the Brazilian Savanna

Restoration Ecology, EarlyView.
Abstract Introduction Grassy wetlands of the Cerrado provide key ecosystem services but remain largely overlooked and are rapidly disappearing, threatened by land use change and climate‐driven changes in hydrological cycles. As restoration initiatives are urgent, reference ecosystems and robust indicators are essential to guide conservation and ...
Andra Carolina Dalbeto, Bruna Helena Campos, Giselda Durigan   +2 more
wiley   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

Regretting mother‐ and fatherhood in Switzerland: Equal parenthood regret but for different reasons

Family Relations, Volume 75, Issue 3, Page 1841-1856, July 2026.
Abstract Objective This article investigates the prevalence of and factors associated with parenthood regret in Switzerland. Background There is increasing evidence that parenthood regrets occur both in mothers and fathers, but little is known about their causes and how they relate to gendered norms and conditions of parenthood.
Larissa Fritsch, Sandra Gilgen
wiley   +1 more source

Hotspots in Cold Climates: Mapping and Evaluating the Conservation of Winter Biodiversity Across the United States

Diversity and Distributions, Volume 32, Issue 6, June 2026.
ABSTRACT Aim To identify hotspots and conservation priorities of biodiversity based on winter‐informed species distribution models for cold‐adapted mammals and birds, and their taxonomic, phylogenetic, and functional richness. Location The United States of America.
Spencer R. Keyser, Jonathan N. Pauli, Volker C. Radeloff, Daniel Fink, Benjamin Zuckerberg   +4 more
wiley   +1 more source

Geodiversity is an inseparable but underutilized aspect of ecological connectivity assessments under climate change

Ecography, Volume 2026, Issue 5, May 2026.
Conservation has shifted towards a climate change adaptation approach in which expected species range shifts are increasingly considered to mitigate effects of climate change and habitat fragmentation on biodiversity. As part of this, ecological connectivity needs to be ensured to support gene flow and viable populations in the face of changing ...
Aino‐Maija Määttänen, Maria Hällfors, Julia Kemppinen   +2 more
wiley   +1 more source

Pandemic Im/mobilities, reproductive injustices, and assisted reproductive technology use among Taiwanese LGBTQ parents

Feminist Anthropology, Volume 7, Issue 1, May 2026.
Abstract This article examines how mobility restrictions imposed by governments during the COVID‐19 pandemic intensified reproductive and mobility injustices. It traces shifting configurations of privilege and inequality within marginalized groups whose reproductive desires remain legally and socially unrecognized.
Sara L. Friedman
wiley   +1 more source