A hepatitis B virus RNA-sensing and RNA-editing-dependent reporter system
The compact genomic organization of hepatitis B virus (HBV) has long hindered the development of reporter viruses that do not compromise viral gene expression and replication. Leveraging the advantage of an RNA-sensing and ADAR-editing-dependent cellular
Liren Sun, Andrew Snedeker, Liudi Tang
doaj +1 more source
Abstract Background: Chronic myeloid leukemia (CML) is defined by the Break point cluster region and Abelson Genes (BCR-ABL) fusion gene, which produces a continuously active tyrosine kinase known as the primary driver responsible for initiating and sustaining the disease.
Aseel Majeed Hameed +2 more
openaire +1 more source
Two novel mutations of the ADAR1 gene in Chinese patients with dyschromatosis symmetrica hereditaria
Chunying, Yuan +10 more
openaire +2 more sources
Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance. [PDF]
Ai ZE +7 more
europepmc +1 more source
ADAR1-circRAB5A-BIP axis governs radiotherapy resistance in colorectal cancer through coordinating protective autophagy and apoptosis. [PDF]
Chen W +5 more
europepmc +1 more source
SFPQ prevents MDA5-mediated activation of innate immunity and preserves cell viability. [PDF]
Zhang H +5 more
europepmc +1 more source
ADAR1 Regulates Alternative Splicing Through an RNA Editing-Independent Mechanism. [PDF]
Sagredo EA +9 more
europepmc +1 more source
Mutations in the ADAR1 gene in 2 Chinese families with dyschromatosis symmetrica hereditaria
G.L. Zhang +7 more
openaire +1 more source
Z-nucleic acid-mediated PANoptosis in infection, inflammation, and cancer. [PDF]
Thapa N +5 more
europepmc +1 more source
Enhancing targeted strategies for cancer immunotherapy by elucidating mRNA processing mechanisms. [PDF]
Lu X, Gan W, Yuan J, Chen Z.
europepmc +1 more source

