Results 1 to 10 of about 549,681 (254)

Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus

Cell Reports, 2018
Summary: RNA-editing mechanisms, which induce nucleotide substitution in the RNA, increase transcript and protein diversities. Editing dysregulation has been shown to lead to grave outcomes, and transcriptome-wide aberrant RNA editing has been found in ...
Shalom Hillel Roth, Miri Danan-Gotthold, Meirav Ben-Izhak, Gideon Rechavi, Cyrille J. Cohen, Yoram Louzoun, Erez Y. Levanon   +6 more
doaj   +1 more source

RNA Polymerase RPOTp is Involved in C‐to‐U RNA Editing at Multiple Sites in Arabidopsis Chloroplasts

Advanced Science
RPOTp is the nuclear‐encoded plastid‐targeted RNA polymerase and plays a crucial role in chloroplast gene expression. Transcripts in plant organelles are altered by the conversion of cytidine (C) to uridine (U) at specific positions through RNA editing ...
Nadia Ahmed Ali, Wenjian Song, Yayi Zhang, Jiani Xing, Kexing Su, Xingxing Sun, Yujia Sun, Yizhou Jiang, Dianxing Wu, Xiaobo Zhao   +9 more
doaj   +1 more source

Targeted RNA base editing for therapeutic: mechanisms and advances

Pharmaceutical Science Advances
RNA base editing, which enables RNA base modification through effector proteins guided by targeting systems, is a powerful technology to correct disease-associated point mutations.
Weikai Yan, Xiaocheng Weng
doaj   +1 more source

RNA editing in Parkinson's disease: emerging mechanisms, translational potential, and current challenges. [PDF]

Front Neurosci
Liu S, Wu A.
europepmc   +1 more source

Site-specific neoepitope induction by RNA editing reprograms tumor immunogenicity. [PDF]

Front Immunol
Liu S, Dong C, Chen L, Yan J, Luo X, Huang H, Qiu Z, Gan X, Yang J, Zhu J, Xiong C, Huang L, Wang L, Yang Z, Meng Z, Yi S, Chen Y, Zuo C, Leng Q, Wang X.   +19 more
europepmc   +1 more source

Correction: Regulation of oncogenic C-terminal truncated p53β protein isoform expression by SRSF3-UPF1 splicing and surveillance axis

Cell & Bioscience
Jiwon Jeong, Dawon Hong, Tae Young Park, Jung Hur, Taeyoung Koo, Sunjoo Jeong   +5 more
doaj   +1 more source

Multi-Tissue Genetic Regulation of RNA Editing in Pigs. [PDF]

Adv Sci (Weinh)
Pan X, Gong W, Cai X, Teng J, Cai J, Zeng H, Ayalew W, Shen Q, Zhong Z, Wang Y, Zhang W, Tian Y, Xu D, Gao Y, Yin H, Zhang Y, Hou J, Zhou T, Li J, Fang L, Yuan X, Zhang Z.   +21 more
europepmc   +1 more source

ADAR1 Regulates Alternative Splicing Through an RNA Editing-Independent Mechanism. [PDF]

Int J Mol Sci
Sagredo EA, Karlström V, Blanco A, Moraga P, Vergara M, Jarvelin AI, Visa N, Marcelain K, Castello A, Armisén R.   +9 more
europepmc   +1 more source

Two codes of RNA editing by deamination in human diseases. [PDF]

Exp Mol Med
Min DJ, Lee S, Lee YS, Cho J.
europepmc   +1 more source

RNA editing: an emerging frontier in cancer therapy - explorations, opportunities, and challenges. [PDF]

Int J Surg
Chen J, Sun Q, Gong N, Du Z, Zhao Z, Ding D, Zhang H, Yan Q, Yuan S, Jiang S.   +9 more
europepmc   +1 more source