Results 81 to 90 of about 868,215 (381)

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

The Domestic Violence Component of the New York Task Force Report on Women in the Courts: An Evaluation and Assessment of New York City Courts [PDF]

open access: yes, 1992
This piece contains the findings of a survey conducted to evaluate the impact of the New York Task Force On Women in the Court\u27s Report in the area of domestic violence and of the progress that has taken place since the Report\u27s publication.
Eaton, Sarah, Hyman, Ariella
core   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman   +5 more
wiley   +1 more source

SINTESIS DAN KARAKTERISASI FILM SELULOSA-PEG (Polyethylene Glycol) 400 DENGAN PENAMBAHAN MINYAK ADAS SEBAGAI PENGEMAS BUAH DAN SAYUR [PDF]

open access: yes, 2018
Penelitian ini bertujuan untuk 1) mengetahui karakteristik film selulosa terbaik dengan penambahan PEG 400 dan minyak adas berdasarkan karakterisasi menggunakan uji mekanik, foto permukaan, dan uji ketahanan air, 2) mengetahui hasil efektivitas film ...
Utami, Rini
core  

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

open access: yesAdvanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang   +6 more
wiley   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

open access: yesAdvanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang   +13 more
wiley   +1 more source

Soil management in organic fruit growing [PDF]

open access: yes, 2000
In the EU-standards you will find a period of three years for converting your orchard from conventional into organic. But conversion of your way of thinking about the orchard system and conversion of your root system and soil will take double time.
Bloksma, Joke
core  

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li   +16 more
wiley   +1 more source

Forecasting Root Rot Disease through Predictive Microbial Functional Profiling

open access: yesAdvanced Science, EarlyView.
Predicting soil‐borne disease moves beyond observation with a framework that elevates microbial functional genes into reliable forecasting biomarkers. By coupling targeted qPCR assays for core stress‐response genes with machine learning, this method detects root rot risks in pre‐symptomatic soils with over 80% accuracy.
Chuan You   +11 more
wiley   +1 more source

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