Results 111 to 120 of about 101,310 (266)

Water‐Dispersible Ruthenium Nanocatalyst for Carbonyl Reduction With D2 or T2 in Aqueous Media

Angewandte Chemie, EarlyView.
We report the synthesis and characterization of water‐dispersible ruthenium nanoparticles that catalyze the reductive deuteration and tritiation of carbonyl compounds in aqueous media, enabling efficient access to a broad range of isotopically labeled polar molecules, including cyclic peptides, antibody‐drug conjugate linkers, pegylated derivatives ...
Elisa Martinelli, Rafael Jiménez Rioboo, Remo Weck, Sophie Feuillastre, Luis M. Martínez‐Prieto, Grégory Pieters, Volker Derdau   +6 more
wiley   +2 more sources

Image Quality Assessment of Diffusion-Weighted Imaging (DWI) and Its Impact on Apparent Diffusion Coefficient (ADC) as a Quantitative Imaging Biomarker for Predicting Response to Neoadjuvant Chemotherapy in High-Risk Early Breast Cancer. [PDF]

Tomography
Li W, Wilmes LJ, Carmona-Bozo J, Le NN, Chung M, Gibbs JE, Onishi N, Price E, Joe BN, Kornak J, Chenevert TL, Malyarenko D, Bolan PJ, Partridge SC, Hylton NM.   +14 more
europepmc   +1 more source

Single‐Step Analog In‐Memory Matrix Computation in Three‐Dimensional Circuits

Advanced Intelligent Systems, EarlyView.
A wooden model illustrates a 3D memristive array designed for single‐step kernel convolutions. It shows how two‐dimensional input data are mapped into the 3D array and convolved in parallel with stored kernels. Color‐coded connection points represent programmed memory‐element values, with each color corresponding to a specific kernel weight.
Alireza Jaberi Rad, Koushik Kumar, Fatemeh Kiani, Yi Huang, Ali Abdel‐Maksoud, Zheshun Xiong, Yunzhi Ling, Wuyu Zhao, Qiangfei Xia   +8 more
wiley   +1 more source

A Blue Emissive Heavy Atom‐Free Multiresonant Thermally Activated Delayed Fluorescent Emitter Shows Ultra‐Fast Reverse Intersystem Crossing

Angewandte Chemie, EarlyView.
The extended π‐system and low‐lying n‐π∗ transition endow DDOBDiKTa with a synergistic combination of strong spin‐orbit coupling, small reorganization energy and small ΔEST, enabling this blue boron‐nitrogen‐carbonyl hybrid emitter to achieve a fast kRISC of 6.34 × 106 s−1 together with OLEDs showing small efficiency roll‐off, with EQEmax/EQE10000 of ...
Wenrui Wang, Hassan Hafeez, Sen Wu, Aidan P. McKay, David B. Cordes, Ifor D. W. Samuel, Eli Zysman‐Colman   +6 more
wiley   +2 more sources

Dynamic monitoring of antibody drug conjugates targeting TROP2 or HER2 in breast cancer using circulating tumor cells. [PDF]

Proc Natl Acad Sci U S A
Mishra A, Abelman RO, Cunneely Q, Putaturo V, Deshpande AA, Bell R, Seider EM, Xu KH, Shan M, Kelly J, Huang SB, Rieur O, Knape J, Gopinathan KA, Kikkeri K, Edd JF, Walsh J, Dai CS, Ellisen LW, Ting DT, Nieman L, Toner M, Bardia A, Haber DA, Maheswaran S.   +24 more
europepmc   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

AI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury, Kandarpa Kumar Sarma, Lachit Dutta   +2 more
wiley   +1 more source

Clinical Value of a Novel Apparent Diffusion Coefficient-Based Bi-Color Map for Detecting Clinically Significant Prostate Cancer: A Retrospective Study. [PDF]

Cancers (Basel)
Okada M, Araki Y, Hirasawa Y, Nagao G, Kashima T, Hayashi K, Satake N, Saito K, Ohno Y.   +8 more
europepmc   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Programmed death 1 antibody drug conjugates (PD 1 ADCs): Innovations in overcoming resistance and enhancing immune mediated antitumor activity. [PDF]

Transl Oncol
Tian Z.
europepmc   +1 more source

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

Annals of Neurology, EarlyView.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber, Ricardo Hernández Arriaza, Dylan Reil, Manon Muntaner, Junyoung Park, Benjamin Grenier‐Boley, Marc Hulsman, Philippe Amouyel, Céline Bellenguez, Camille Charbonnier, Jean‐François Deleuze, Orio Dols‐Icardo, John Hardy, Henne Holstege, Gaël Nicolas, Simon Mead, Michael Wagner, Alfredo Ramirez, Rebecca Sims, John van Swieten, Julie Willams, Jean‐Charles Lambert, Chaitan Khosla, Yann Le Guen, Michael D Greicius   +24 more
wiley   +1 more source