Results 141 to 150 of about 101,310 (266)

Multiomic characterization of malignant pulmonary nodules and development of a methylation-based diagnostic Model. [PDF]

J Transl Med
Zhou W, Xie T, Wu Q, Song M, Weng J, Zhang J, Gao X, Zheng M, Wang Z, Zhou Y, Li Y.   +10 more
europepmc   +1 more source

The Mechanism of Visible‐Light Photochemical Rearrangements of Conjugated Amide Enolates

Chemistry – A European Journal, EarlyView.
Visible light irradiation of extended enolates of N‐benzylamides leads to homolytic C─N Bond cleavage, generating a biradical. Computational and mechanistic studies suggest rapid radical recombination within a solvent cage to give either ring‐expanded or rearranged products. ABSTRACT Deprotonation of conjugated amides forms colored solutions of lithium
James Mortimer, William Terry‐Wright, Basile F. E. Curchod, Jonathan Clayden   +3 more
wiley   +1 more source

Development of an Active Chimeric IL13Rα2 ADC for Diffuse Intrinsic Pontine Glioma. [PDF]

Immunotargets Ther
Lian X, Allanson VJ, Rasmussen SV, Chauhan S, Tan GK, Morrow P, Hanson K, Lian EB, Haight AR, Hoshino T, Liu X, Berlow NE, Keller C, Lian Y.   +13 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Association of neurite orientation dispersion and density imaging with cognitive impairment in nasopharyngeal carcinoma patients with radiation-induced temporal lobe injury. [PDF]

Front Hum Neurosci
Zeng W, Wen Q, Su Y, Peng Q, Yan Z, Chen X, Yan X, Qin H, Li J, Mao J.   +9 more
europepmc   +1 more source

A Co‐Designed Implicit‐Reset Path PFD and Current Mismatch Compensated CP Enabling Sub‐0.5% Mismatch and Dead Zone‐Free for Low‐Spur PLLs

International Journal of Circuit Theory and Applications, EarlyView.
A co‐designed implicit‐reset phase‐frequency detector (PFD) and nonlinear amplifier‐assisted charge pump (CP) achieve dead zone‐free operation from 10 MHz to 4.7 GHz with < 0.5% current mismatch without calibration, enabling −80 dBc of reference spur and 0.50 ps of RMS jitter in a 180 nm of CMOS PLL.
A. Ghaemnia, Jincheng Yang, Xiaojiong Fei, G. Zhang   +3 more
wiley   +1 more source

Associations Between Apparent Diffusion Coefficient Values and Histopathologic Prognostic Factors in Breast Cancer: A Retrospective Study. [PDF]

Int J Breast Cancer
Mahdavi Sabet F, Zeinalkhani F, Forghani S, Kamali Hakim P, Zeinalkhani H, Tahanian F.   +5 more
europepmc   +1 more source

An Ultra‐Low‐Power Biopotential Acquisition Analog Front‐End Chip for Wearable Devices

International Journal of Circuit Theory and Applications, EarlyView.
A 0.8‐V, 1.2‐μW biopotential AFE combines a chopper‐stabilized CCIA with dual‐time‐scale EDO management. The slow DSL preserves > 1 GΩ input impedance, whereas an event‐triggered fast‐recovery path shortens return to the linear range after abrupt electrode‐offset disturbances. ABSTRACT A 0.8‐V, 1.2‐μW biopotential analog front‐end (AFE) IC is presented
Zhang Xin, Yang Tianqi, Xu Wei, Wang Shun, Xiaoxi Ma   +4 more
wiley   +1 more source

Radiomics to understand pre-treatment tumor biology for resectable non-small cell lung cancer. [PDF]

Front Oncol
Zollinger B, Pham D, Suzuki K.
europepmc   +1 more source

Digital Rights Activism in Multilevel Governance

European Policy Analysis, EarlyView.
ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley   +1 more source