Results 151 to 160 of about 176,033 (310)

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

Advanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao, Zhiwei Cheng, Kai Tian, Mengxiong Sun, Zhuoying Wang, Ming Jiao, Jens Luebeck, Kaiyuan Zhu, Xiao Zhang, Dongqing Zuo, Hongsheng Wang, Chongren Wang, Jiakang Shen, Xiaojun Ma, Gangyang Wang, Zongyi Wang, Jing Han, Kaiyuan Liu, Haoran Mu, Weiqi Ma, Yongyong Ren, Shibing Guo, Huangxin Tu, Lingfeng Yu, Yining Tao, Yu Lv, Hui Lu, Owen S. Chapman, Rishaan Kenkre, Lukas Chavez, Zhengdong Cai, Yuqin Yang, Wei Sun, Yafei Jiang, Yingqi Hua   +34 more
wiley   +1 more source

A Systematic Review of Mechanisms, Incidence, and Management of Trastuzumab Deruxtecan Induced ILD/Pneumonitis in Solid Tumors

Drug Design, Development and Therapy
Dehua Liao,1 Jiwen Zhang,1,2 Ting Yan,1 Yun Chen,1 Yilan Fu,1 Ning Xie,3,* Minghui Long1,* 1Department of Pharmacy, Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, People’s ...
Liao D, Zhang J, Yan T, Chen Y, Fu Y, Xie N, Long M   +6 more
doaj  

Hardware‐Native Gaussian Sampling With Probabilistic Ising Machines for Modern Communication Paradigms

Advanced Science, EarlyView.
Probabilistic Ising machines are introduced as hardware‐native Gaussian samplers for edge communication workloads. Tunable variance and sampling density enable accurate distributions for Falcon‐class post‐quantum signatures and diffusion‐based semantic communication.
Davi Rodrigues, Andrea Grimaldi, Deborah Volpe, Youwei Bao, Shuhan Yang, Eleonora Grassucci, Giulio Siracusano, Massimo Chiappini, Mario Carpentieri, Hyunsoo Yang, Giovanni Finocchio   +10 more
wiley   +1 more source

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source

An Environmental Stable Ionogel‐Based Smart Glove System for Integrated Underwater Communication and Safety Warning

Advanced Science, EarlyView.
This study develops a smart glove by integrating a P(BZMA‐co‐HEA)/IL ionogel with a reconfigurable FPCB for underwater communication and real‐time safety warning. The network‐constrained ionic soft‐space regulation strategy enables mechanical reliability, environmental stability, and sensing adaptability, while the modular FPCB sensor array simplifies ...
Xiaoqin Li, Jianwen Liu, Wenhao Yang, Wenjing Yue, Nam‐Young Kim, Young‐Kee Shin, Song Gao, Eun‐Seong Kim, Yang Li   +8 more
wiley   +1 more source

Cell-Based Assay Development and Standardization for Antibody-Drug Conjugates. [PDF]

BioTech (Basel)
Sun D, Hsu A, Long H, Qin K, Welch J, McCann S, Cheng ZJ.   +6 more
europepmc   +1 more source

Gradient‐Oxidized Bacterial Cellulose for Self‐Sustained Soil Moisture Sensing

Advanced Science, EarlyView.
An asymmetric encapsulated bacterial cellulose device integrates a gradient‐oxidized BC framework with a LiCl‐doped Ecoflex hygroscopic layer, enabling self‐powered soil moisture monitoring through directional ion transport. The device sustains stable hydrovoltaic output, supports deep‐learning humidity classification, and fully biodegrades in soil ...
Nan Zhou, Jing Li, Xiang Xu, Senyuan Ye, Bin Chen, Shuang Wu, Duo Xu, Keshuai Liu, Chong Gao, Weilin Xu, Can Ge   +10 more
wiley   +1 more source

Negative Correlation Between ADC Values and GPC3 Expression in Hepatocellular Carcinoma: A Quantitative Diffusion-Weighted Imaging Study. [PDF]

J Hepatocell Carcinoma
Fu Z, Huang Y, Liu Y, Man Y.
europepmc   +1 more source

Contact‐Free Human‐Machine Interfaces via Printed Thermopile Infrared Arrays

Advanced Science, EarlyView.
Can a printed sheet locate and sense a fingertip without being touched? Fully printed, flexible thermoelectric arrays convert the infrared from a hovering finger directly into voltage, with no external power. Aerosol‐jet‐printed silver mirrors partially shield each pixel, creating a local temperature gradient.
Zirui Wang, Nan Luo, Amrutha Bose, Muhammad Irfan Khan, Jiayi Liu, Leon Viktor Klinder, Leonard Franke, Mohamed Hussein, Uli Lemmer, Md Mofasser Mallick   +9 more
wiley   +1 more source

Emerging Memory and Device Technologies for Hardware‐Accelerated Model Training and Inference

Advanced Electronic Materials, EarlyView.
This review investigates the suitability of various emerging memory technologies as compute‐in‐memory hardware for artificial intelligence (AI) applications. Distinct requirements for training‐ and inference‐centric computing are discussed, spanning device physics, materials, and system integration.
Yoonho Cho, Dae‐won Kim, Yujin Kim, Jung‐Heum Na, Yuwon Jeong, Dong‐Yeop Lee, Shinhyun Choi   +6 more
wiley   +1 more source