Results 41 to 50 of about 6,383 (147)

Scalable low‐cost seabed landers: the missing link for sustained, integrated, long‐term observations in dynamic shallow seas

Remote Sensing in Ecology and Conservation, EarlyView.
Seabed landers, when equipped with a range of biotic and abiotic sensors, offer a non‐invasive and cost‐effective solution for ecosystem‐scale monitoring of Essential Biodiversity Variables (EBVs) and Essential Ocean Variables (EOVs) in dynamic shallow seas.
Arienne Calonge, Roeland Develter, Carlota Muñiz, Clea Parcerisas, Jan Reubens, Wieter Boone, Klaas Deneudt, Elisabeth Debusschere   +7 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source

Reconnaissance‐Scale Methods for the Identification of Groundwater Discharge to Streams

Groundwater Monitoring &Remediation, EarlyView.
Abstract Identifying groundwater discharge locations is critical for understanding and monitoring groundwater contributions to streams in terms of water quantity and quality. Streams and rivers are under increasing strain from factors, including increased urbanization, agricultural land use, groundwater extraction, and climate change, which can alter ...
Corey M. Zanatta, Andrew J. Wiebe, David L. Rudolph   +2 more
wiley   +1 more source

CLDN18.2 in pancreatic ductal adenocarcinoma: Biomarker assessment, spatial heterogeneity and therapeutic modality selection

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review presents a framework for selecting Claudin 18.2 (CLDN18.2)‐directed treatment modalities in pancreatic ductal adenocarcinoma according to tumour antigen coverage and spatial distribution. Representative assessment at baseline and reassessment after progression can guide treatment adaptation over time.
Ruyu Tan, Zhexin Zhang, Jiaxin Wang, Roland Andersson, Daniel Ansari, Jinfei Chen   +5 more
wiley   +1 more source

Open Ocean Biogeochemical Impacts of Extreme Terrestrial Precipitation

Geophysical Research Letters, Volume 53, Issue 18, 28 September 2026.
Abstract Extreme events reshape ocean ecosystems with significant implications for nutrient and carbon cycling. Here, we demonstrate that flooding on land can be a significant driver of biogeochemical variability in the open ocean, even in relatively dry climates.
Shailja Gangrade, Mara A. Freilich, Élise Beaudin, Kelly M. A. Luis, Inés M. Leyba, Melissa M. Omand, Sarah E. Lang, Jeff S. Bowman, Larry O’Neill, Dante A. Capone   +9 more
wiley   +1 more source

Grid Turbulence Measurements with an Acoustic Doppler Current Profiler

Fluids
The motivation for this study is to investigate the abilities and limitations of a Nortek Signature1000 acoustic Doppler current profiler (ADCP) regarding fine-scale turbulence measurements.
Trygve K. Løken, David Lande-Sudall, Atle Jensen, Jean Rabault   +3 more
doaj   +1 more source

Referencing geostrophic velocities using ADCP data Referencing geostrophic velocities using ADCP data

Scientia Marina, 2010
Acoustic Doppler Current Profilers (ADCPs) have proven to be a useful oceanographic tool in the study of ocean dynamics. Data from D279, a transatlantic hydrographic cruise carried out in spring 2004 along 24.5°N, were processed, and lowered ADCP (LADCP)
Isis Comas-Rodríguez, Alonso Hernández-Guerra, Elaine L. McDonagh   +2 more
doaj   +1 more source

Surface Expression of the Kuroshio Extension Northern Recirculation Gyre

Geophysical Research Letters, Volume 53, Issue 17, 16 September 2026.
Abstract The Northern Recirculation Gyre (NRG) of the Kuroshio Extension (KE) has traditionally been viewed as subsurface‐intensified and difficult to identify at the sea surface. We combine a 2016–2025 subsurface mooring record, satellite altimetry, Argo trajectory‐based velocities, and historical near‐bottom velocities to reassess the sea‐surface ...
Haihong Guo, Mengze Song, Zhaohui Chen
wiley   +1 more source

Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells.

PLoS Pathogens
Antibody-dependent cellular phagocytosis (ADCP) has been implicated in protection against HIV-1. However, methods for measuring ADCP currently rely on the phagocytosis of gp120- or gp41-coated beads that do not reflect physiologically relevant ...
Brian J Snow, Nida K Keles, Michael W Grunst, Sanath Kumar Janaka, Ryan T Behrens, David T Evans   +5 more
doaj   +1 more source