Results 51 to 60 of about 6,383 (147)

Constructing immune and prognostic features associated with ADCP in hepatocellular carcinoma and pan-cancer based on scRNA-seq and bulk RNA-seq

Frontiers in Immunology
AimDespite the significant therapeutic outcomes achieved in systemic treatments for liver hepatocellular carcinoma (LIHC), it is an objective reality that only a low proportion of patients exhibit an improved objective response rate (ORR) to current ...
Zhengwei Zhang, Yuying Li, Zhen Quan, Yapeng Li, Liying Zhu, Shibo Sun, Xiaoning Chen   +6 more
doaj   +1 more source

Observation of Yanai Wave Excitation by Tropical Instability Waves in the Equatorial Pacific

Geophysical Research Letters, Volume 53, Issue 17, 16 September 2026.
Abstract Yanai waves are observed in the central equatorial Pacific at 436–864 m depth, below the Equatorial Undercurrent. Applying maximum likelihood estimation to shipboard ADCP measurements enables identification of Yanai wave signals from irregularly sampled observations.
Arachaporn Anutaliya, Caitlin B. Whalen, Gunnar Voet, Anna‐Lena Deppenmeier, Amy F. Waterhouse, Caique Dias Luko, Arnaud Le Boyer   +6 more
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, Volume 38, Issue 49, 1 September 2026.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

High-Frequency Surface Wave Radar Current Measurement Corrections via Machine Learning and Towed Acoustic Doppler Current Profiler Integration

Applied Sciences
This paper proposes an algorithm based on the long short-term memory (LSTM) network to improve the quality of high-frequency surface wave radar current measurements.
Zhaomin Xiong, Chunlei Wei, Fan Yang, Langfeng Zhu, Rongyong Huang, Jun Wei   +5 more
doaj   +1 more source

A Sample-Sparing Multiplexed ADCP Assay

Frontiers in Immunology, 2019
Antibodies serve as the primary correlate of protection following most clinically approved vaccines and are thought to confer protection in part through their ability to block (neutralize) infection.
Audrey L. Butler, Jonathan K. Fallon, Galit Alter   +2 more
doaj   +1 more source

MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity

JCI Insight, 2023
Myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) is an inflammatory demyelinating CNS condition characterized by the presence of MOG autoantibodies.
Soumya S. Yandamuri, Beata Filipek, Abeer H. Obaid, Nikhil Lele, Joshua M. Thurman, Naila Makhani, Richard J. Nowak, Yong Guo, Claudia F. Lucchinetti, Eoin P. Flanagan, Erin E. Longbrake, Kevin C. O’Connor   +11 more
doaj   +1 more source

Variation of Zooplankton Mean Volume Backscattering Strength from Moored and Mobile ADCP Instruments for Diel Vertical Migration Observation

Applied Sciences, 2019
Zooplankton can be detected by using acoustic Doppler current profiler (ADCP) instruments through acquiring the mean volume backscattering strength (MVBS) data.
Angga Dwinovantyo, Henry M. Manik, Tri Prartono, Susilohadi Susilohadi, Tohru Mukai   +4 more
doaj   +1 more source

Targeting a membrane-proximal epitope on mesothelin increases the tumoricidal activity of a bispecific antibody blocking CD47 on mesothelin-positive tumors

mAbs, 2020
Mesothelin (MSLN) is a cell surface glycoprotein overexpressed in several solid malignancies, including gastric, lung, mesothelioma, pancreatic and ovarian cancers.
Eric Hatterer, Xavier Chauchet, Françoise Richard, Leticia Barba, Valéry Moine, Laurence Chatel, Lucile Broyer, Guillemette Pontini, Tereza Bautzova, Flora Juan, Sebastien Calloud, Nicolas Bosson, Maud Charreton, Krzysztof Masternak, Vanessa Buatois, Limin Shang   +15 more
doaj   +1 more source

Spatial and Temporal Variation in Drivers of Saltmarsh Eco‐Geomorphic Evolution: Field Insights From the St. Lawrence Estuary, Canada

Earth Surface Processes and Landforms, Volume 51, Issue 9, September 2026.
Field campaigns establish a novel hydro‐eco‐geomorphic database for St. Lawrence Estuary saltmarshes; foundations to predict ecosystem evolution in an understudied region. Documented spatial and temporal variability in vegetation traits, inundation dynamics and sediment supply warrants further investigation in saltmarsh modelling frameworks.
Acacia Markov, Jacob Stolle, Ioan Nistor, Abolghasem Pilechi   +3 more
wiley   +1 more source

From temporal variability to integrated metabolic balance: Interpreting total alkalinity and dissolved inorganic carbon relationships in dynamic coral reef ecosystems

Limnology and Oceanography Letters, Volume 11, Issue 5, September 2026.
Abstract Linear regressions between total alkalinity (TA) and dissolved inorganic carbon (DIC) are widely used to infer the balance between net ecosystem calcification (NEC) and net ecosystem production (NEP) in coral reefs. Using high‐frequency carbonate chemistry observations from an Australian reef flat and simple numerical models, we show that TA ...
Tyler Cyronak, Yuichiro Takeshita, Rebecca Albright, Ken Caldeira, Bradley Eyre, Alyssa Griffin, David A. Koweek, Jennifer Mallon, Manoela Romano de Orte, Kai G. Schulz, Kennedy Wolfe   +10 more
wiley   +1 more source