Results 51 to 60 of about 1,033 (153)
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics [PDF]
, 2016 Mastitis, inflammation of the mammary gland, is the most common and costly disease of dairy cattle in the western world. It is primarily caused by bacteria, with Streptococcus uberis as one of the most prevalent causative agents.
Burchmore, Richard +10 more
core +1 more source
Adenylyl cyclases (ACs) in GtoPdb v.2023.1 [PDF]
, 2023 Adenylyl cyclase, E.C. 4.6.1.1, converts ATP to cyclic AMP and pyrophosphate. Mammalian membrane-delimited adenylyl cyclases (nomenclature as approved by the NC-IUPHAR Subcommittee on Adenylyl cyclases [11]) are typically made up of two clusters of six ...
Dessauer, Carmen W. +3 more
core +2 more sources
Reproductive consequences of electrolyte disturbances in domestic animals [PDF]
, 2022 Electrolyte balance is essential to maintain homeostasis in the body. The most crucial electrolytes are sodium (Na+), potassium (K+), magnesium (Mg2+), chloride (Cl?), and calcium (Ca2+).
Araujo, Jose Pedro +3 more
core +1 more source
PLoS ONE, 2012 Various types of genomic data (e.g., SNPs and mRNA transcripts) have been employed to identify risk genes for complex diseases. However, the analysis of these data has largely been performed in isolation.
Hongbao Cao +3 more
doaj +1 more source
Journal of Clinical Investigation, 2020 Mechanisms mediating the cardioprotective actions of glucagon-like peptide 1 (GLP-1) were unknown. Here, we show in both ex vivo and in vivo models of ischemic injury that treatment with GLP-1(28-36), a neutral endopeptidase-generated (NEP-generated ...
M. Siraj +13 more
semanticscholar +1 more source
A Novel Gene Required for Male Fertility and Functional CATSPER Channel Formation in Spermatozoa [PDF]
, 2014 Summary Calcium signaling is critical for successful fertilization. In spermatozoa, capacitation, hyperactivation of motility, and the acrosome reaction are all mediated by increases in intracellular Ca2+.
Chung, Jean-Ju +4 more
core +1 more source
Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue [PDF]
, 2016 Previous work indicated that lysine-specific demethylase 1 (Lsd1) can positively regulate the oxidative and thermogenic capacities of white and beige adipocytes.
Arrigoni, Laura +17 more
core +3 more sources
The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm [PDF]
, 2016 Sperm capacitation is required for fertilization. At the molecular level, this process is associated with fast activation of protein kinase A. Downstream of this event, capacitating conditions lead to an increase in tyrosine phosphorylation. The identity
Alvau, Antonio +13 more
core +1 more source
Maternal Transmission Ratio Distortion in two Iberian pig varieties [PDF]
, 2020 [EN] Transmission ratio distortion (TRD) is defined as the allele transmission deviation from the heterozygous parent to the offspring from the expected Mendelian genotypic frequencies. Although TRD can be a confounding factor in genetic mapping studies,
Casellas, Joaquim +7 more
core +3 more sources
Zoological Letters, 2019 Background CatSper is a sperm-specific calcium ion (Ca2+) channel, which regulates sperm flagellar beating by tuning cytoplasmic Ca2+ concentrations. Although this Ca2+ channel is essential for mammalian fertilization, recent bioinformatics analyses have
Francisco Romero, Takuya Nishigaki
doaj +1 more source