Results 71 to 80 of about 1,136 (81)

Dysregulated hepatic alcohol metabolism: a key factor involved in the pathogenesis of alcohol-associated liver disease. [PDF]

Am J Physiol Gastrointest Liver Physiol
Srinivasan M, Kota S, Bhopale K, Caracheo A, Kaphalia L, Linares J, Romsdahl T, Russell W, Popov V, Boor P, Kaphalia B.   +10 more
europepmc   +1 more source

Unveiling the Therapeutic Potential: A Peptide Drug Conjugate's Influence on Transcription and Translation in Ocular Fibrosis Modulation. [PDF]

ACS Omega
Suresh Babu J, Gaikwad KB, Arumugam P, Sharma J, Elchuri SV, George R, Janakiraman N.   +6 more
europepmc   +1 more source

Dynamic changes in the transcriptome and metabolome of pig ovaries across developmental stages and gestation. [PDF]

BMC Genomics
Pan B, Chai J, Fei K, Zheng T, Jiang Y.
europepmc   +1 more source

Comparative transcriptome analysis of bull X- and Y-spermatozoa. [PDF]

Sci Rep
Umar SIU, Prasad S, Naskar S, Das PJ, Sharma M, Pattanayak A, Murasing DK, Bhadana VP, Rakshit S.   +8 more
europepmc   +1 more source

Novel biallelic ADCY10 variants cause asthenozoospermia with excessive residual cytoplasm and hydronephrosis in humans

Reproductive BioMedicine Online
Could the novel mutations in ADCY10 cause asthenozoospermia and absorptive hypercalciuria in humans, and the potential pathogenesis?Whole-exome sequencing and Sanger sequencing were conducted to identify potential pathogenic variants in two unrelated Pakistani families. Reverse transcription polymerase chain reaction was utilized to assess the mutation
Aurang Zeb, Menglei Yang, Nisar Ahmad, Huan Zhang, Wasim Shah, Khalid Khan, Meftah Uddin, Asma Mansoor, Fazal Rahim, Ansar Hussain, Imtiaz Ali, Tanveer Abbas, Muhammad Zubair, Ihsan Khan, Qinghua Shi   +14 more
openalex   +3 more sources

Two novel heterozygous ADCY10 variants identified in Chinese pediatric patients with absorptive hypercalciuria: case report and literature review

Journal of Genetics
Absorptive hypercalciuria (AH) is a prevalent cause of kidney stones, and the adenylate cyclase 10 (ADCY10) gene is a rare causative gene of AH. This study aims to investigate the genotypic and phenotypic characteristics of patients with AH caused by ADCY10 gene mutations.
Yucheng Ge, Yukun Liu, Ruichao Zhan, Zhenqiang Zhao, Wenying Wang, Ye Tian   +5 more
openalex   +3 more sources

Jinwu Jiangu Capsule alleviates rheumatoid arthritis symptoms by regulating the ADCY10 and cAMP/RANKL pathways

Journal of Ethnopharmacology
Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects joints and damages other tissues, including the heart, kidneys, lungs, digestive system, eyes, skin and nervous system. Jinwu Jiangu Capsule (JWJG) is effective in tonifying kidneys, activating blood circulation, and dispelling wind and dampness.
Qiuyi Wang, Yuzheng Yang, Xuemei Yuan, Feng Luo, Yi Ling, Changming Chen, Ying Huang, Runyue Huang, Wukai Ma, Xueming Yao   +9 more
openalex   +3 more sources

Faculty Opinions recommendation of Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2022
Bharath Srinivasan
openalex   +2 more sources