Results 81 to 90 of about 978 (151)

Potential impact of primate‐specific SVA retrotransposons during the evolution of human cognitive function. [PDF]

open access: yes, 2017
The SVA family of hominid-specific non-LTR retrotransposon comprises the youngest group of transposable elements in the human genome. The propagation of the most ancient SVA subfamily took place about 13.5 million years ago, and the youngest SVA ...
Bubb, VJ   +5 more
core   +1 more source

Molecular mechanisms of mammalian sperm capacitation, and its regulation by sodium‐dependent secondary active transporters

open access: yesReproductive Medicine and Biology, Volume 23, Issue 1, January/December 2024.
Abstract Background Mammalian spermatozoa have to be “capacitated” to be fertilization‐competent. Capacitation is a collective term for the physiological and biochemical changes in spermatozoa that occur within the female body. However, the regulatory mechanisms underlying capacitation have not been fully elucidated. Methods Previously published papers
Gen L. Takei
wiley   +1 more source

Soluble Adenylyl Cyclase Activity Is Necessary for Retinal Ganglion Cell Survival and Axon Growth

open access: yesJournal of Neuroscience, 2012
cAMP is a critical second messenger mediating activity-dependent neuronal survival and neurite growth. We investigated the expression and function of the soluble adenylyl cyclase (sAC, ADCY10) in CNS retinal ganglion cells (RGCs).
R. Corredor   +5 more
semanticscholar   +1 more source

Genetic etiology of Asthenozoospermia: A review

open access: yesFiyz̤, 2019
Background: Asthenozoospermia, as the most prevalent cause of male infertility, is defined as low percentage of progressively motile spermatozoa per ejaculate.
Arvand Akbari   +3 more
doaj  

Intracellular Ca2+ threshold reversibly switches flagellar beat off and on†

open access: yesBiology of Reproduction, 2018
Sperm motility is essential for fertilization. The asymmetry of flagellar beat in spermatozoa is finely regulated by intracellular calcium concentration ([Ca2+]i).
C. Sánchez-Cárdenas   +6 more
semanticscholar   +1 more source

Non-canonical regulation of glycogenolysis and the Warburg phenotype by soluble adenylyl cyclase

open access: yesbioRxiv, 2020
Cyclic AMP is produced in cells by two very different types of adenylyl cyclases: the canonical transmembrane adenylyl cyclases (tmACs, ADCY1∼9) and the evolutionarily more conserved soluble adenylyl cyclase (sAC, ADCY10).
Jung-Chin Chang   +8 more
semanticscholar   +1 more source

Coxiella burnetii and Leishmania Mexicana Residing Within Similar Parasitophorous Vacuoles Elicit Disparate Host Responses [PDF]

open access: yes, 2015
Coxiella burnetii is a bacterium that thrives in an acidic parasitophorous vacuole (PV) derived from lysosomes. Leishmania mexicana, a eukaryote, has also independently evolved to live in a morphologically similar PV.
Cambronne, Eric D.   +7 more
core   +1 more source

Molecular mechanism underlying the action of zona-pellucida glycoproteins on mouse sperm [PDF]

open access: yes, 2020
Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca2+ influx via the sperm-specific, pH-sensitive Ca2+ channel CatSper.
Balbach, M.   +13 more
core   +1 more source

Home - About - Disclaimer - Privacy