Results 81 to 90 of about 1,033 (153)
MedComm, Volume 5, Issue 7, July 2024.Periodontitis accompanied by type 2 diabetes exhibits significant hypomethylation of Fc gamma receptor‐related genes compared with periodontitis. Periodontitis accompanied by type 2 diabetes shows a notable increase in C>T base substitutions within Fc gamma receptor‐related genes compared with periodontitis.
Junho Kang +6 more
wiley +1 more source
Coxiella burnetii and Leishmania Mexicana Residing Within Similar Parasitophorous Vacuoles Elicit Disparate Host Responses [PDF]
, 2015 Coxiella burnetii is a bacterium that thrives in an acidic parasitophorous vacuole (PV) derived from lysosomes. Leishmania mexicana, a eukaryote, has also independently evolved to live in a morphologically similar PV.
Cambronne, Eric D. +7 more
core +1 more source
Identification and validation of a novel anoikis‐related prognostic model for prostate cancer
Molecular Genetics &Genomic Medicine, Volume 12, Issue 4, April 2024.Our study has identified a novel anoikis‐related signature consisting of four genes, which demonstrated significant prognostic value for PCa patients. Our findings suggest that this signature could serve as a valuable tool for predicting patient outcomes and guiding personalized treatment strategies for PCa.
Peipei Zhang +5 more
wiley +1 more source
Genetic Testing and FOX News [PDF]
, 2022 Genetic testing is transforming kidney care, arguably with similar impact as the adoption of kidney biopsies in the 1950s. It is incumbent on nephrologists to teach the genetics of kidney disease and the accessibility of genetic testing.
Bichet, Daniel G, Bockenhauer, Detlef
core
The Journal of Gene Medicine, Volume 26, Issue 1, January 2024.Based on anoikis‐related genes, we developed a risk prediction model to provide individualized and precise treatment for lung adenocarcinoma patients. Patients in different risk groups need to be targeted for treatment. Abstract Background One of the most prevalent malignancies in the world is lung adenocarcinoma (LUAD), with a large number of people ...
Yue Liu +6 more
wiley +1 more source
Supplementary data and simulation code - "ADCY10 is a key regulator of cell cycle control"
, 2021 Woranush Warunya +3 more
openalex +4 more sources
Reproductive Medicine and Biology, Volume 23, Issue 1, January/December 2024.Abstract Background Mammalian spermatozoa have to be “capacitated” to be fertilization‐competent. Capacitation is a collective term for the physiological and biochemical changes in spermatozoa that occur within the female body. However, the regulatory mechanisms underlying capacitation have not been fully elucidated. Methods Previously published papers
Gen L. Takei
wiley +1 more source
Soluble Adenylyl Cyclase Activity Is Necessary for Retinal Ganglion Cell Survival and Axon Growth
Journal of Neuroscience, 2012 cAMP is a critical second messenger mediating activity-dependent neuronal survival and neurite growth. We investigated the expression and function of the soluble adenylyl cyclase (sAC, ADCY10) in CNS retinal ganglion cells (RGCs).
R. Corredor +5 more
semanticscholar +1 more source
Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways [PDF]
, 2013 Ca2+ ionophore A23187 is known to induce the acrosome reaction of mammalian spermatozoa, but it also quickly immobilizes them. Although mouse spermatozoa were immobilized by this ionophore, they initiated vigorous motility (hyperactivation) soon after ...
Darszon, Alberto +6 more
core +2 more sources
, 2019 Inside the female genital tract, mammalian sperm undergo a maturation process called capacitation, which primes the sperm to navigate across the oviduct and fertilize the egg.
Hansen, J. +8 more
core +1 more source