Results 151 to 160 of about 32,310 (305)

A Higher radix architecture for quantum carry-lookahead adder. [PDF]

Sci Rep, 2023
Wang S, Baksi A, Chattopadhyay A.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Novel approximate adaptive carry lookahead adder for error resilient applications with generic method for error analysis. [PDF]

Sci Rep
Joshi V, Mane P.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Substantial Genetic Differentiation Within and Between Populations of the European Adder (<i>Vipera berus</i>) in Baden-Württemberg, Germany. [PDF]

Ecol Evol
Schmid PL, Grünewald J, Förschler MI, Griebeler EM.   +3 more
europepmc   +1 more source

High-speed and energy-efficient asynchronous carry look-ahead adder. [PDF]

PLoS One, 2023
Balasubramanian P, Liu W.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Biochemical characterisation and substrate-specific proteolytic diversity of venom metalloproteinases in African puff adders. [PDF]

Toxicon X
Wilkinson MC, Modahl CM, Waterhouse DTK, Saviola A, Albulescu LO, Tianyi FL, Kazandjian TD, Wüster W, Theart F, Oluoch GO, Harrison RA, Casewell NR.   +11 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Low power reprogrammable DNA basecaller with an efficient HMM accelerator for real time nanopore sequencing. [PDF]

Sci Rep
Shahraki AS, Magierowski S, Abbasi M, Kamarposhti MA.   +3 more
europepmc   +1 more source