Results 21 to 30 of about 5,636,748 (390)

Dopamine, behavior, and addiction [PDF]

Journal of Biomedical Science, 2021
AbstractAddictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals have only unlearned reflexes; they lack learned seeking and learned avoidance.
Roy A. Wise, Roy A. Wise, Chloe J. Jordan   +2 more
openaire   +4 more sources

Bleachorexia-an addictive behavior to tooth bleaching: a case report. [PDF]

Clin Case Rep, 2018
Lee DK, Kastl C, Chan DCN.
europepmc   +3 more sources

The impact of COVID-19 pandemic on mental burden and quality of life in medical students – results of an online survey

GMS Journal for Medical Education, 2023
Objectives: Changes in academic conditions due to the COVID-19 pandemic are potential stressors for medical students and can make them vulnerable for the development of psychiatric disorders.Previous pandemics had a negative impairment on well-being due ...
Halfmann, Marie, Wetzel, Lea, Castioni, Noah, Kiefer, Falk, König, Sarah, Schmieder, Astrid, Koopmann, Anne   +6 more
doaj   +1 more source

Effectiveness and cost-effectiveness of sector-independent treatment coordination for people with substance-related disorders following an online assessment (ASSIST): study protocol for a randomized controlled trial

Trials, 2022
Background The implementation of person-centred, need-oriented and flexible care for people with substance-related problems is often insufficient, in large part due to the complexity of addiction support services among different providers. A standardized
Annabel S. Mueller-Stierlin, Jeanette Röhrig, Christian Goetzl, Michael Krausz, Jutta Lehle, Elke Prestin, Vanessa-Emily Schoch, Lorenz Sutter, Jean Westenberg, Maurice Cabanis   +9 more
doaj   +1 more source

ON-ICE trial: Investigation of the combined effects of oxytocin and naltrexone on stress-induced and alcohol cue-induced craving in alcohol use disorder–Study protocol of a phase II randomised double-blind placebo-controlled parallel-group trial

BMJ Open, 2022
Introduction Although alcohol dependence (AD) is highly prevalent, only few medications are approved for its treatment. While currently approved medications, such as naltrexone (NTX), reduce craving and relapse risk to a certain extent, new approaches ...
Falk Kiefer, Johannes Krisam, Christina Klose, Bettina C Thomas, Sabine Vollstaedt-Klein, Sina Zimmermann, Ronald Limprecht, Manuel Stenger, Madeleine Pourbaix, Marcel Ries, Anne Koopmann, Bernd Lenz, Patrick Bach   +12 more
doaj   +1 more source

G-CuP: the effect of a forced oral glucose intake on alcohol craving and mesolimbic cue reactivity in alcohol dependence—study protocol of a randomized, double-blind, placebo-controlled crossover study

Trials, 2022
Background Multiple studies indicate that a lower plasma level of the acetylated form of the appetite-regulating hormone ghrelin and higher plasma levels of insulin lead to a reduction in subjective alcohol craving and a reduced mesolimbic cue reactivity
Lea Wetzel, Madeleine Pourbaix, Alisa Riegler, Anna-Maria Pfeifer, Iris Reinhard, Sabine Hoffmann, Sabine Vollstädt-Klein, Falk Kiefer, Wolfgang Sommer, Jan Malte Bumb, Patrick Back, Anne Koopmann   +11 more
doaj   +1 more source

A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders

Frontiers in Psychiatry, 2022
RationaleChildhood maltreatment (CM) leads to detrimental mental health outcomes, such as substance use disorders (SUD). This study examined prevalence and severity of all five types of CM with respect to specific substances and sex in treatment-seeking ...
Sarah Gerhardt, Katharina Eidenmueller, Sabine Hoffmann, Sabine Hoffmann, Nina K. Bekier, Patrick Bach, Derik Hermann, Derik Hermann, Anne Koopmann, Wolfgang H. Sommer, Wolfgang H. Sommer, Wolfgang H. Sommer, Falk Kiefer, Falk Kiefer, Falk Kiefer, Sabine Vollstädt-Klein, Sabine Vollstädt-Klein   +16 more
doaj   +1 more source

Effects of chess-based cognitive remediation training as therapy add-on in alcohol and tobacco use disorders: protocol of a randomised, controlled clinical fMRI trial

BMJ Open, 2022
Background Alcohol and tobacco use disorders (AUD, TUD) are frequent, both worldwide and in the German population, and cognitive impairments are known to facilitate instances of relapse.
Sarah Gerhardt, Sabine Vollstädt-Klein, Gereon Lex, Jennifer Holzammer, Damian Karl, Alfred Wieland, Roland Schmitt, Ainoa Jiménez Recuero, Juan Antonio Montero, Tillmann Weber   +9 more
doaj   +1 more source

An Emotion Regulation and Impulse Control (ERIC) Intervention for Vulnerable Young People: A Multi-Sectoral Pilot Study

Frontiers in Psychology, 2021
Objective: There is a demonstrated link between the mental health and substance use comorbidities experienced by young adults, however the vast majority of psychological interventions are disorder specific.
Kate Hall, Kate Hall, George Youssef, George Youssef, George Youssef, Angela Simpson, Angela Simpson, Elise Sloan, Elise Sloan, Liam Graeme, Natasha Perry, Richard Moulding, Richard Moulding, Amanda L. Baker, Alison K. Beck, Petra K. Staiger, Petra K. Staiger   +16 more
doaj   +1 more source

Virtual reality: a powerful technology to provide novel insight into treatment mechanisms of addiction

Translational Psychiatry, 2021
Due to its high ecological validity, virtual reality (VR) technology has emerged as a powerful tool for mental health research. Despite the wide use of VR simulations in research on mental illnesses, the study of addictive processes through the use of VR
Massimiliano Mazza, Kornelius Kammler-Sücker, Tagrid Leménager, Falk Kiefer, Bernd Lenz   +4 more
doaj   +1 more source