Results 41 to 50 of about 3,790,514 (280)

Technology prevention of addictive behavior in children as part of a healthy lifestyle

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2014
Purpose : to develop a technology of social and educational prevention of addictive behavior in children as part of the organization of a healthy lifestyle.
A.D. Zolotova
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Synthesis and Characterization of Biocompatible Manganese‐Doped Titania Nanoparticles and Its Application to Single‐Cell Nanoencapsulation

Advanced Materials Interfaces, EarlyView.
Biocompatible Mn‐doped TiO2 nanozymes integrate TiO2 stability with Mn redox activity, enabling dopamine‐mediated cell‐surface polymerization and single‐cell nanoencapsulation while maintaining high colloidal stability, low ROS generation, and excellent cellular compatibility.
Filip Kozłowski, Nayoung Kim, Hyunwoo Choi, Geoffrey Daniel, Gulaim A. Seisenbaeva, Insung S. Choi, Vadim G. Kessler   +6 more
wiley   +1 more source

Online Therapy for Addictive Behaviors [PDF]

CyberPsychology & Behavior, 2005
Clinicians working in the field of addictive behaviors cannot afford to ignore the Internet. Psychological advice, help, and treatment for addicts are no exceptions, with both counseling and psychotherapy entering the computer age. This paper reviews the main issues in the area and approaches the discussion acknowledging that online therapy has to be ...
openaire   +3 more sources

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

Advanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji, Tao Li, Guoqiang Lei, Huichun Luo, Xiuqian Guo, Jiao Xiang, Tao Shi, Weitang Liu, Yuxin Zhang, Xiaoyu Liao, Shutao Zhao, Jiayun Wu, Wangao Zhang, Wenhui Liu, Chuanglong He, Shuo Chen, Tao Wu, Ke Ma   +17 more
wiley   +1 more source

Investigation of the combined effects of cannabidiol plus naltrexone on alcohol craving in alcohol dependence: study protocol of a phase II randomised, double-blind, placebo-controlled, parallel-group trial – ICONICplus Trial

BMJ Open
Introduction Alcohol dependence (AD) is highly prevalent and has severe consequences on health and quality of life. However, the efficacy of approved pharmacotherapies such as naltrexone (NTX) remains limited, highlighting the need for novel ...
Falk Kiefer, Christina Klose, Bettina C Thomas, Sabine Vollstaedt-Klein, Marietta Kirchner, Anne Koopmann, Bernd Lenz, Patrick Bach, Sina Vetter, Julia Weinberg, Paul Thalmann, Marlen Pfisterer, Torsten Kölsch, Selma Oesterle, Tobias Link   +14 more
doaj   +1 more source

An exploration into “do-it-yourself” (DIY) e-liquid mixing: Users' motivations, practices and product laboratory analysis

Addictive Behaviors Reports, 2019
Background: E-liquids are commercially available and manufactured, however some users of e-cigarettes prefer to prepare them at home (Do-it-Yourself; DIY) using individual ingredients.
Sharon Cox, Noel J. Leigh, Taylor S. Vanderbush, Emma Choo, Maciej L. Goniewicz, Lynne Dawkins   +5 more
doaj   +1 more source

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Potential of D-cycloserine in the treatment of behavioral and neuroinflammatory disorders in Parkinson's disease and studies that need to be performed before clinical trials

Kaohsiung Journal of Medical Sciences, 2012
Hyperactivation of glutamatergic N-methyl-D-aspartate (NMDA) receptors has been implicated in the excitotoxicity and pathophysiology of Parkinson's disease (PD).
Cornelius Rainer Pawlak, Fu-Shih Chen, Fu-Ying Wu, Ying-Jui Ho   +3 more
doaj   +1 more source

Changes of consultation-liaison psychiatry practice in Italian general hospitals: A comparative 20-year multicenter study

Frontiers in Psychiatry, 2022
IntroductionConducted under the auspices of the Italian Society of Consultation Liaison Psychiatry (SIPC) the aim of this study was to describe the characteristics of Consultation Liaison Psychiatry (CLP) activity in Italy (SIPC-2—2018) over the past 20 ...
Luigi Zerbinati, Luigi Zerbinati, Laura Palagini, Laura Palagini, Matteo Balestrieri, Martino Belvederi Murri, Martino Belvederi Murri, Rosangela Caruso, Rosangela Caruso, Armando D’Agostino, Armando D’Agostino, Maria Ferrara, Maria Ferrara, Silvia Ferrari, Silvia Ferrari, Antonino Minervino, Paolo Milia, Maria Giulia Nanni, Maria Giulia Nanni, Stefano Pini, Pierluigi Politi, Matteo Porcellana, Matteo Rocchetti, Ines Taddei, Tommaso Toffanin, Tommaso Toffanin, Luigi Grassi, Luigi Grassi, Italian Society of Consultation-Liaison Psychiatry, Jessica Bellucci, Jessica Bellucci, Emilio Bergamelli, Victor Attilio Campagna, Melissa Cherubini, Melissa Cherubini, Federica Folesani, Federica Folesani, Marta Gancitano, Marta Gancitano, Francesca Giannetti, Gianluca Giovanna, Benedetta Gullotta, Benedetta Gullotta, Lucia Massa, Giulia Montardi, Giulia Montardi   +45 more
doaj   +1 more source