Results 111 to 120 of about 13,595 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Spectral theory of fluctuations in time-average statistical mechanics of reversible and driven systems

open access: yesPhysical Review Research, 2020
We present a spectral-theoretic approach to time-average statistical mechanics for general, nonequilibrium initial conditions. We consider the statistics of bounded, local additive functionals of reversible as well as irreversible ergodic stochastic ...
Alessio Lapolla   +2 more
doaj   +1 more source

Genetic Generalized Additive Models

open access: yesCoRR
Accepted to NAFIPS ...
Kaaustaaub Shankar, Kelly Cohen
openaire   +2 more sources

Generalized Model of Courier with Additional Restrictions

open access: yesBulletin of the South Ural State University. Series "Mathematical Modelling, Programming and Computer Software", 2016
Summary: Mathematical model of process of sequential choice of permutation variants and fulfilment of works complex with complication at the expense of the operations coupling on different time intervals and preceding conditions is constructed. Routization problem with constraints and costs functions depending on tasks list is considered.
Chentsov, A. A., Chentsov, A. G.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A 25.1% Efficient Stand‐Alone Solar Chloralkali Generator Employing a Microtracking Solar Concentrator

open access: yesGlobal Challenges, 2017
Chlorine is a large‐scale chemical commodity produced via the chloralkali process, which involves the electrolysis of brine in a membrane‐based electrochemical reactor.
Enrico Chinello   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Counting Z2Z4Z8-additive codes

open access: yes, 2019
In Algebraic Coding Theory, all linear codes can be described by generator matrices. Any linear code has different generator matrices. It is important to find the number of the generator matrices for the construction of these codes.
Balikci, Kemal, Caliskan, Basri
core  

The method based on binary MC(s,r) under additive distortions for estimating the model parameters of Geffe's generator

open access: yes, 2010
Statistical estimators for the parameters of the binary Markov chain with par- tial connections under additive distortions are presented.
Piatlitski, A. I.
core   +1 more source

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