Results 151 to 160 of about 567,714 (357)
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
CAMIEM: Compact Additively Manufactured Innovative Electric Motor [PDF]
New manufacturing methods are needed to obtain innovative electric motor designs that have much higher power densities and/or efficiencies compared to the current state-of-the-art.
Halbig, Michael C. +1 more
core +1 more source
Control architectures for Industrial Additive Manufacturing Systems [PDF]
, 2015 Industrial Additive Manufacturing technologies are increasingly being employed in manufacturing environments, yet there has been little consideration of these in terms of manufacturing systems.
Eyers, Daniel Roy
core
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
3D designed battery-free wireless origami pressure sensor
Microsystems & Nanoengineering, 2022 Taeil Kim +4 more
doaj +1 more source
A design framework for additive manufacturing based on the integration of axiomatic design approach, inverse problem-solving and an additive manufacturing database [PDF]
, 2018 Additive manufacturing has emerged as an integral part of modern manufacturing because of its unique capabilities and has already found its application in various domains like aerospace, automotive, medicine and architecture.
Chennamkulam Renjith, Sarath
core +2 more sources
dr0wned - Cyber-Physical Attack with Additive Manufacturing [PDF]
arXiv, 2016 Additive manufacturing (AM), or 3D printing, is an emerging manufacturing technology that is expected to have far-reaching socioeconomic, environmental, and geopolitical implications. As use of this technology increases, it will become more common to produce functional parts, including components for safety-critical systems.
arxiv
Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
Demystifying “absolute truths” of additive manufacturing [PDF]
Authors received funding from the European Institute of Innovation and Technology (EIT) \u2013 Project Smart WAAM: Microstructural Engineering and Integrated Non-Destructive Testing.
Oliveira, J. P., Santos, Telmo G.
core +1 more source
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source