Results 131 to 140 of about 1,616,356 (309)
Multifunctional composite microgels: From structural design to biomedical applications
Microgels, micrometer-sized hydrogel particles, have emerged as versatile platforms for biomedical applications. Recent advances have driven the development of composite microgels that integrate polymers, nanomaterials, and bioactive agents to achieve ...
Yanli Cai +8 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Mathematical approaches for track analysis and process optimization in additive manufacturing
Additive manufacturing demands precise control of track formation and process parameters. Here we show a unified mathematical framework that links key variables to track geometry: we derive analytical expressions for solid and liquid contact angles ...
Mahdi Alishavandi +2 more
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Additive Manufacturing (AM) for metallic applications continues to redefine how complex, high-performance components are designed and fabricated across a wide range of sectors, including the aerospace, biomedical, and automotive fields, etc [...
Rǎzvan Pǎcurar, Petru Berce
core +1 more source
Supply chain perspective on additive manufacturing
Current research on Additive Manufacturing (AM) has focused primarily on the technological aspects in terms of improving engineering feasibility and product quality. The increasing maturity of AM technology is not going to incrementally provide another
Ma, Shuang +2 more
core +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
In-situ elimination of β-flecks in additively manufactured Ti-3.5 wt% Fe alloy
Meta-stable β titanium alloys that feature excellent mechanical properties are of great interest for a range of engineering applications. In particular, Fe containing titanium alloy is one of the most promising alloy systems because Fe is the most ...
Dongze Chen +4 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Synergistic strengthening mechanisms of
Ti–6Al–4V samples were fabricated via in-situ rolling-assisted laser directed energy deposition, and the effects of rolling load and heat treatment on microstructure and tensile properties were studied.
Jixin Yang +6 more
doaj +1 more source

