Results 121 to 130 of about 1,616,356 (309)
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Dimensional metrology and non-destructive testing for additive manufacturing
, 2017 State-of-the-art review on dimensional metrology and non-destructive testing for additive ...
Simone Carmignato, Filippo Zanini
core
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Off the Grid: A new strategy for material-jet 3D printing with enhanced sub-droplet resolution
Additive Manufacturing LettersDrop-on-Demand additive manufacturing could offer a facile solution for scalable on-site manufacturing. With an increasing number of functional materials available for this technology, there are growing opportunities for applications, such as electronics.
Oliver Nelson-Dummett +7 more
doaj +1 more source
Engineering Tomorrow: Optimised Materials and Surfaces for Additive Manufacturing
Focusing on advancements in additive manufacturing, this Special Issue explores the role of novel materials and surface technologies in improving functionality, performance, and sustainability.
Tomislav Cigula +2 more
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Comparison of Different Additive Manufacturing Methods Using Optimized Computed Tomography [PDF]
, 2016 Additive manufacturing (AM) allows for fast fabrication of three dimensional objects with the possibility of use of considerably less resources than would be the case in traditional manufacturing.
Shah, Paras +2 more
core +1 more source
3D designed battery-free wireless origami pressure sensor
Microsystems & Nanoengineering, 2022 Taeil Kim +4 more
doaj +1 more source