Results 71 to 80 of about 128,882 (238)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Exploring the frontiers of metal additive manufacturing in orthopaedic implant development

open access: yesMethodsX
This paper provides a thorough analysis of recent advancements and emerging trends in the integration of metal additive manufacturing (AM) within orthopedic implant development. With an emphasis on the use of various metals and alloys, including titanium,
Senthil Maharaj Kennedy   +2 more
doaj   +1 more source

Porous composite with negative thermal expansion obtained by photopolymer additive manufacturing

open access: yes, 2015
Additive manufacturing (AM) could be a novel method of fabricating composite and porous materials having various effective performances based on mechanisms of their internal geometries.
Kitamura, Mitsuru   +2 more
core   +2 more sources

A framework of energy consumption modelling for additive manufacturing using Internet of Things [PDF]

open access: yes, 2017
The topic of ‘Industry 4.0’ has become increasingly popular in manufacturing and academia since it was first published. Under this trending topic, researchers and companies have pointed out many related capabilities required by current manufacturing ...
Grosvenor, Roger, Liu, Ying, Qin, Jian
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Recent advances in metal hybrid additive manufacturing: a comprehensive review

open access: yesInternational Journal of Extreme Manufacturing
Metal additive manufacturing (AM) holds significant potential for the rapid prototyping of complex parts in the aerospace, defense, and military industries, biomedicine, and other fields. Despite its advantages over conventional manufacturing methods, AM
Yu Lu   +10 more
doaj   +1 more source

Micro-milling Machinability of DED Additive Titanium Ti-6Al-4V [PDF]

open access: yes, 2017
This work investigates the micro-milling machinability of Ti-6Al-4V alloy produced by a Laser Engineered Net Shaping (LENS) additive manufacturing (AM) process with a specific focus on surface quality, cutting forces and burr formation.
Annoni, Massimiliano   +3 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A Global Administrative Law Bibliography [PDF]

open access: yes, 2005
Additive Manufacturing (AM) comprises a family of different technologies that build up parts by adding materials layer by layer at a time based on a digital 3D solid model.
Beiker Kair, Alexandros   +1 more
core   +1 more source

The Impact of Additive Manufacturing Technologies on Industrial Spare Parts Strategies [PDF]

open access: yes, 2018
The paper aims to investigate potential benefits and the applicability of additive manufacturing (AM) technologies for spare parts management in the automotive industry.
Beiderbeck, Daniel   +2 more
core   +1 more source

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