Results 71 to 80 of about 33,834 (307)

Strengthening the Sustainability of Additive Manufacturing through Data‐Driven Approaches and Workforce Development

Advanced Intelligent Systems, 2021
The additive manufacturing (AM) industry is rapidly developing and expanding, thereby becoming an important and integral component of the digital revolution in manufacturing practices.
Tianjiao Li, Jingjie Yeo
doaj   +1 more source

Review on Quality Control Methods in Metal Additive Manufacturing

Applied Sciences, 2021
Metal additive manufacturing (AM) has several similarities to conventional metal manufacturing, such as welding and cladding. During the manufacturing process, both metal AM and welding experience repeated partial melting and cooling, referred to as ...
Jungeon Lee, Hyung Jun Park, Seunghak Chai, Gyu Ri Kim, Hwanwoong Yong, Suk Joo Bae, Daeil Kwon   +6 more
doaj   +1 more source

Hybrid manufacturing – integrating traditional manufacturers with additive manufacturing (AM) supply chain

Additive Manufacturing, 2018
Abstract The ever-growing applications of Additive Manufacturing (AM) in the production of low volume- high value metal parts can be attributed to improving AM processing capabilities and complex design freedom. However, secondary post-processing using traditional processes such as machining, grinding, heat treatment and hot isostatic pressing, i.e.,
Danielle Strong, Michael Kay, Brett Conner, Thomas Wakefield, Guha Manogharan   +4 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Exploring the frontiers of metal additive manufacturing in orthopaedic implant development

MethodsX
This paper provides a thorough analysis of recent advancements and emerging trends in the integration of metal additive manufacturing (AM) within orthopedic implant development. With an emphasis on the use of various metals and alloys, including titanium,
Senthil Maharaj Kennedy, Vasanthanathan A, Amudhan K   +2 more
doaj   +1 more source

Feasibility evaluation of a new lattice for porous surface design in additive manufacturing medical implants under interfacial tensile bonded testing

, 2023
Porous titanium implant surfaces fabricated with suitable porosity and size using additive manufacturing (AM) can enhance bone–implant stability. There is a critical need to understand the biomechanical performance of porous (lattice) type implants to ...
Wang, Yu-Tzu;Chang, Chun-Ming;Liu, Pei-Hsin;Lin, Chun-Li
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Supply chain perspective on additive manufacturing

, 2018
Current research on Additive Manufacturing (AM) has focused primarily on the technological aspects in terms of improving engineering feasibility and product quality. The increasing maturity of AM technology is not going to incrementally provide another
Ma, Shuang, Tan, Morris Kwang Jiang, Chen, Songlin   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source