Results 71 to 80 of about 142,725 (307)

Automation and manufacturing of smart materials in additive manufacturing technologies using Internet of Things towards the adoption of industry 4.0 [PDF]

E3S Web of Conferences
Business 4.0 emphasizes mass personalization and customisation. Even though additive manufacturing (AM) technologies are capable of producing single items, they are not suitable for 3D printing in large quantities. They are at a disadvantage because they
Kumar Voruganti Naresh, Hassan Muntather M., Pant Ruby, Hima Bindu V., Sivasankar G.   +4 more
doaj   +1 more source

Strengthening the Sustainability of Additive Manufacturing through Data‐Driven Approaches and Workforce Development

Advanced Intelligent Systems, 2021
The additive manufacturing (AM) industry is rapidly developing and expanding, thereby becoming an important and integral component of the digital revolution in manufacturing practices.
Tianjiao Li, Jingjie Yeo
doaj   +1 more source

Review on Quality Control Methods in Metal Additive Manufacturing

Applied Sciences, 2021
Metal additive manufacturing (AM) has several similarities to conventional metal manufacturing, such as welding and cladding. During the manufacturing process, both metal AM and welding experience repeated partial melting and cooling, referred to as ...
Jungeon Lee, Hyung Jun Park, Seunghak Chai, Gyu Ri Kim, Hwanwoong Yong, Suk Joo Bae, Daeil Kwon   +6 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Micro-milling Machinability of DED Additive Titanium Ti-6Al-4V [PDF]

, 2017
This work investigates the micro-milling machinability of Ti-6Al-4V alloy produced by a Laser Engineered Net Shaping (LENS) additive manufacturing (AM) process with a specific focus on surface quality, cutting forces and burr formation.
Annoni, Massimiliano, Bonaiti, Giuseppe, Kapoor, Shiv, Parenti, Paolo   +3 more
core   +1 more source

Overhang analysis fabricated using fused deposition modelling technique [PDF]

, 2020
Additive manufacturing (AM) is a process using layer by layer additive technique to fabricate the entire 3D models into a functional component. One of the most popular AM technology is fused deposition modeling (FDM) that utilizes thermoplastic filaments
Abdul Kadir, Aini Zuhra, Mazlan, Siti Nur Humaira, Wahab, Md Saidin, Yusof, Yusri   +3 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Exploring the frontiers of metal additive manufacturing in orthopaedic implant development

MethodsX
This paper provides a thorough analysis of recent advancements and emerging trends in the integration of metal additive manufacturing (AM) within orthopedic implant development. With an emphasis on the use of various metals and alloys, including titanium,
Senthil Maharaj Kennedy, Vasanthanathan A, Amudhan K   +2 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source