Results 151 to 160 of about 6,934,820 (306)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Corrigendum: Additive manufacturing of Al2O3 ceramics with MgO/SiC contents by laser powder bed fusion process

Frontiers in Chemistry, 2023
Asif Ur Rehman, Asif Ur Rehman, Asif Ur Rehman, Abid Ullah, Abid Ullah, Abid Ullah, Tingting Liu, Rashid Ur Rehman, Metin U. Salamci, Metin U. Salamci, Metin U. Salamci   +10 more
doaj   +1 more source

Controlled Synthesis of Tri‐ and Multi‐Doped Graphene

Advanced Materials Interfaces
Graphene possesses exceptional electrical, mechanical, and thermal properties, yet its lack of a bandgap and chemically inert surface continue to limit practical applications.
Maria Hasan, Alicja Bachmatiuk, Gražyna Simha Martynková, Karla Čech Barabaszová, Mark Hermann Rümmeli   +4 more
doaj   +1 more source

An Overview of Additive Manufacturing Technologies-A Review to Technical Synthesis in Numerical Study of Selective Laser Melting. [PDF]

Materials (Basel), 2020
Razavykia A, Brusa E, Delprete C, Yavari R.   +3 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Additive Manufacturing Technologies and Applications [PDF]

, 2017
The present Special Issue proposes articles in the area of Additive Manufacturing with particular attention to the different employed technologies and the several possible applications. The main investigated technologies are the Selective Laser Sintering (SLS) and the Fused Deposition Modelling (FDM).
Carlo Giovanni Ferro (Ed.), Paolo Maggiore (Ed.), Salvatore Brischetto (Ed.)   +2 more
openaire  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Additive Manufacturing of Metal Materials for Construction Engineering: An Overview on Technologies and Applications

Additive manufacturing, better known as 3D printing, is an innovative manufacturing technique which allows the production of parts, with complex and challenging shapes, layer by layer mainly through melting powder particles (metallic, polymeric, or ...
Francesca Romana Andreacola, Ilaria Capasso, Giuseppe Brando   +2 more
core   +1 more source