Results 141 to 150 of about 156,720 (303)

Additive technologies in the polymer components manufacturing for aerospace structures: design and optimization methods

open access: yesАвіаційно-космічна техніка та технологія
The subject matter of the article is additive manufacturing technologies used in the fabrication of polymer components for aerospace structures. The goal is to develop a comprehensive methodology focused on optimizing the design of polymer components ...
Oleksandr Dzhurynskyi
doaj   +1 more source

A New Consumerism: The influence of social technologies on product design [PDF]

open access: yes, 2014
Social media has enabled a new style of consumerism. Consumers are no longer passive recipients; instead they are assuming active and participatory roles in product design and production, facilitated by interaction and collaboration in virtual ...
de Vere, I
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Segregation-guided alloy design via tailored solidification behavior

open access: yesMaterials Today Advances
This study presents an alloy design perspective guided by elemental segregation during solidification to determine the site-specific chemistry and related local thermodynamic properties of dendritic microstructures. This was accomplished via manipulation
Ahmet Turnali   +10 more
doaj   +1 more source

3D printing: A qualitative assessment of applications, recent trends and the technology's future potential

open access: yes, 2015
Additive manufacturing (AM) or 3D printing is currently one of the most discussed emerging technologies coming to market with a potentially disruptive power.
Bechthold, Laura   +8 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The production and materials of mouthguards: Conventional vs additive manufacturing - A systematic review

open access: yesHeliyon
This investigation presents a critical analysis of mouthguard production, focusing on the evaluation of conventional vs additive manufacturing methods, the materials involved, and aspects such as their failure and prevention.
Victor Paes Dias Gonçalves   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy