Results 131 to 140 of about 156,720 (303)

Innovative additive technologies in the creation of structural elements of aircraft and spacecraft

Технічна інженерія
In modern aerospace manufacturing, additive technologies have become very important because of their potential for fast and efficient production of complex structural elements.
V.M. Orel, O.F. Salenko, P.P. Melnychuk
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Oral drug delivery systems using core-shell structure additive manufacturing technologies: a proof-of-concept study. [PDF]

J Pharm Pharmacol, 2021
Zhang J, Xu P, Vo AQ, Repka MA.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Corrigendum: Additive manufacturing of Al2O3 ceramics with MgO/SiC contents by laser powder bed fusion process

Frontiers in Chemistry, 2023
Asif Ur Rehman, Asif Ur Rehman, Asif Ur Rehman, Abid Ullah, Abid Ullah, Abid Ullah, Tingting Liu, Rashid Ur Rehman, Metin U. Salamci, Metin U. Salamci, Metin U. Salamci   +10 more
doaj   +1 more source

Automated Additive Construction (AAC) for Earth and Space Using In-situ Resources [PDF]

, 2016
Using Automated Additive Construction (AAC), low-fidelity large-scale compressive structures can be produced out of a wide variety of materials found in the environment.
Ali, Hisham, Andersen, Christian, Burgoyne, Hayden, Chambers, Wesley, Clinton, Raymond, De Kestellier, Xavier, Ebelt, Keye, Gerner, Shai, Hofmann, Douglas, Hogstrom, Kristina, Howe, Scott, Ilves, Erika, Jerves, Alex, Keenan, Ryan, Keravala, Jim, Khoshnevis, Behrokh, Kochmann, Dennis, Lim, Sungwoo, Metzger, Philip, Meza, Lucas, Mueller, Robert P., Nakamura, Takashi, Nelson, Andrew, Partridge, Harry, Pettit, Donald, Pyle, Rod, Reiners, Eric, Shapiro, Andrew, Singer, Russell, Tan, Wei-Lin, Vazquez, Noel, Wilcox, Brian, Zelhofer, Alex   +32 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

STATE AND PROSPECTS FOR DEVELOPMENT OF QUICK PROTOTYPING TECHNOLOGIES IN INDUSTRY. (Part 2)

Наука и техника, 2013
Growth dynamics pertaining to country- and industry branch-wise application of additive technologies is presented in the paper. The paper contains application examples of these technologies with a view of rapid manufacturing.
L. Kolesnikov, G. Mangula, V. Sheleh, A. Iakimovich   +3 more
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

STATE AND PROSPECTS FOR DEVELOPMENT OF RAPID PROTOTYPING TECHNOLOGIES IN INDUSTRY (Part Оne)

Наука и техника, 2013
Growth dynamics pertaining to country- and industry branch-wise application of additive technologies is presented in the paper. The paper contains application examples of these technologies with a view of rapid manufacturing.
L. A. Kolesnikov, G. P. Mangula, V. K. Sheleh, A. M. Iakimovich   +3 more
doaj