Results 51 to 60 of about 6,934,820 (306)

Research progress in additive manufacturing technology of magnesium alloys

Cailiao gongcheng, 2023
Magnesium alloy as the most potential light structural material, has the advantages of high specific strength, specific stiffness and easy recycling, which contributes to the realization of lightweight in the industrial field.
LI Qingzhuang, ZHANG Hanzheng, WANG Shuo, WANG Peng, FENG Mengnan   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Additive Manufacturing Research and Applications

, 2022
Additive Manufacturing (AM) has undergone somewhat of a revolution over the last decade and it has now evolved into a viable industrial manufacturing solution, able to create complex geometries which are unachievable with traditional manufacturing ...
Atila Ertas, Adam Stroud
core   +1 more source

Model for the Prediction of Deformations in the Manufacture of Thin-Walled Parts by Wire Arc Additive Manufacturing Technology [PDF]

, 2021
Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.Gas Metal Arc Welding (GMAW) is a manufacturing technology included within the differentWire Arc Additive Manufacturing alternatives.
Lamikiz, Aitzol, Aitzol Lamikiz, Casuso, Mikel, Fernando Veiga, Eider Aldalur, Suárez, Alfredo, Veiga Suárez, Fernando, Amondarain, Jaime, Trunal Bhujangrao, Bhujangrao, Trunal, Aldalur, Eider, Mikel Casuso, Lamikiz Mentxaka, Aitzol, Veiga, Fernando, Teresa Artaza, Jaime Amondarain, Casuso Lomas, Mikel, Artaza, Teresa, Alfredo Suárez   +18 more
core   +1 more source

Multiscale elemental segregation and post-HIP microstructural evolution in the laser powder bed fusion of IN738LC nickel-based superalloy

Materials & Design
Laser powder bed fusion (LPBF) of the medium-γ′ nickel-based superalloy IN738LC is strongly affected by multiscale elemental segregation, which promotes low-melting interdendritic constituents, defect sensitivity, and a heterogeneous heat-treatment ...
Mahdi Alishavandi, Akın Orhangül, Özgür Duygulu, Haydar Güneş, Rahmi Ünal, Metin U. Salamci   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Investigation on curing strategies for metal binder jetting with Ti-6Al-4V

Additive Manufacturing Letters
Metal binder jetting is a promising manufacturing technology that holds the potential to be a future competition technology to classic laser based additive manufacturing processes.
Kevin Janzen, Timo Rieß, Claus Emmelmann   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source