Results 71 to 80 of about 156,720 (303)

Achieving high strength and ductility in Inconel 718: tailoring grain structure through micron-sized carbide additives in PBF-LB/M additive manufacturing

Virtual and Physical Prototyping
Few attempts have been made so far to develop modifiers for in situ use in Inconel 718 PBF-LB/M fabrication. Reports show an increase in tensile strength compared to unmodified counterparts.
Konrad Gruber, Wojciech Stopyra, Karol Kobiela, Philipp Kohlwes, Jan Čapek, Efthymios Polatidis, Ingomar Kelbassa   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A Gait Pattern Generator for Closed-Loop Position Control of a Soft Walking Robot

Frontiers in Robotics and AI, 2020
This paper presents an approach to control the position of a gecko-inspired soft robot in Cartesian space. By formulating constraints under the assumption of constant curvature, the joint space of the robot is reduced in its dimension from nine to two ...
Lars Schiller, Arthur Seibel, Josef Schlattmann   +2 more
doaj   +1 more source

Modelling methodologies for quality assessment of 3D inkjet printed electronic products [PDF]

, 2016
Purpose of the Fraunhofer Direct Digital Manufacturing Conference is an intellectual exchange between researchers, enterprises and users of Additive Manufacturing technologies in order to gather the latest information about trends, progress, importance ...
Bailey, C., Stoyanov, S., Tilford, T., Tourloukis, G.   +3 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

CVD-Engineered Nano Carbon Architectures: Mechanisms, Challenges, and Outlook

Nanomaterials
Graphitic nanomaterials have emerged as foundational components in nanoscience owing to their exceptional electrical, mechanical, and chemical properties, which can be tuned by controlling dimensionality and structural order.
Maria Hasan, Szymon Abrahamczyk, Muhammad Aashir Awan, Ondřej Sakreida, Alicja Bachmatiuk, Grazyna Simha Martynková, Karla Čech Barabaszová, Mark Hermann Rümmeli   +7 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Research progress and application of additive manufacturing technology for rotorcraft structure

Cailiao gongcheng
The rotorcraft structures have typical characteristics such as small batches， multi-specifications， complex shape and high-performance requirements. Additive manufacturing technologies have the ability to integrally form complex shapes and structures and
HAN Zhenzhong, CHEN Guangchang, LI Wei, HE Peigang, WEN Peigang, YE Shuqun, LIANG Kun, DENG Xudong   +7 more
doaj   +1 more source

Hybrid Prototypes to Assist Modeling Automotive Seats [PDF]

, 2006
The development of new modular seats is an important issue in the automotive industry. However, is very time consuming and costly. Virtual models and hybrid prototypes could accelerate the car seats development process. The hybrid prototypes are mainly
Beira, R., Ferreira, J. C., Madureira, H.   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source