Results 81 to 90 of about 156,720 (303)

CAMIEM: Compact Additively Manufactured Innovative Electric Motor [PDF]

open access: yes
New manufacturing methods are needed to obtain innovative electric motor designs that have much higher power densities and/or efficiencies compared to the current state-of-the-art.
Halbig, Michael C.   +1 more
core   +1 more source

Comparison of production strategies and degree of postponement when incorporating additive manufacturing to product supply chains [PDF]

open access: yes, 2017
The best-selling products manufactured nowadays are made in long series along rigid product value chains. Product repetition and continuous/stable manufacturing is seen as a chance for achieving economies of scale.
Gimeno Feu, Robert   +8 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Additive Manufacturing Technologies and Applications [PDF]

open access: yes, 2017
Additive Manufacturing (AM) Technologies is has become widely popular manufacturing technique in the last 30 years. Additive manufacturing uses 3D Computer Aided Design (CAD) model to manufacture parts layer by layer through adding materials. Additive Manufacturing allows to manufacture complex geometries that cannot be manufactured using conventional ...
Omer Faruk Beyca   +2 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Possibilities of Additive Manufacturing in Medical Use

open access: yesInternational Journal of Engineering and Management Sciences, 2019
Additive Manufacturing has been invented in 1981 at the University of Texas, and to this day it has grown to be the most versatile and promising manufacturing technology in the market, both the industry and health care system has noticed this.
Dániel Szabó
doaj   +1 more source

Survey on Additive Manufacturing, Cloud 3D Printing and Services

open access: yes, 2017
Cloud Manufacturing (CM) is the concept of using manufacturing resources in a service oriented way over the Internet. Recent developments in Additive Manufacturing (AM) are making it possible to utilise resources ad-hoc as replacement for traditional ...
Baumann, Felix W., Roller, Dieter
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Additive manufacturing in maxillofacial reconstruction

open access: yesMATEC Web of Conferences, 2017
In this paper the benefits of using additive manufacturing technologies in maxillofacial reconstruction are highlighted. Based on a real clinical case, the paper describes the manufacture of an implant prototype replacing the right zygomatic bone and a ...
Dincă Luciana Laura   +2 more
doaj   +1 more source

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