Results 61 to 70 of about 156,720 (303)

A Buckingham-Pi dimensionless analysis for melt pool stability and defect prediction in additive manufacturing

open access: yesAdditive Manufacturing Letters
Melt pool instabilities limit the reliability of additive manufacturing. Here, we demonstrate that a minimal Buckingham-π framework, supplemented by a normalized enthalpy (NE) metric, consolidates process outcomes across heat source settings (power ...
Mahdi Alishavandi   +2 more
doaj   +1 more source

Progress in Additive Manufacturing

open access: yesУспехи физики металлов, 2023
The article analyses the current trends in the development of additive manufacturing (AM) technologies. In recent years, the development of additive technologies is one of the industry priorities.
A. V. Volokitin, M. A. Latypova, A. T. Turdaliev, and О. G. Kolesnikova
doaj   +1 more source

Control architectures for industrial additive manufacturing systems [PDF]

open access: yes, 2017
As the emergent technologies of Industrial Additive Manufacturing become increasingly employed in commercial manufacturing environments, challenges arise in terms of how resources of the manufacturing system should be marshalled and controlled for ...
Eyers, Daniel
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Fundamental investigation on the impact of Cu powder oxidation states on processability by powder bed Fusion-Laser Beam/Metal (PBF-LB/M)

open access: yesMaterials & Design
This study introduces targeted oxidation of Cu powders as a strategy to improve both laser power coupling and powder reusability for the PBF-LB/M process.
Arne Röttger   +8 more
doaj   +1 more source

Assessment of the potential economic impact of the use of AM technologies in the cost levels of manufacturing and stocking of spare part products [PDF]

open access: yes, 2018
Additive manufacturing (AM) technologies are appropriate manufacturing technologies to produce low rotation products of high added value. Products in the spare parts business usually have discontinuous demand levels of reduced numbers of parts.
Gomà Ayats, Joan Ramon   +3 more
core   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Latest Developments in Industrial Hybrid Machine Tools that Combine Additive and Subtractive Operations [PDF]

open access: yes, 2018
Hybrid machine tools combining additive and subtractive processes have arisen as a solution to increasing manufacture requirements, boosting the potentials of both technologies, while compensating and minimizing their limitations.
Arrizubieta Arrate, Jon Iñaki   +4 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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