Results 61 to 70 of about 6,934,820 (306)

A Buckingham-Pi dimensionless analysis for melt pool stability and defect prediction in additive manufacturing

Additive Manufacturing Letters
Melt pool instabilities limit the reliability of additive manufacturing. Here, we demonstrate that a minimal Buckingham-π framework, supplemented by a normalized enthalpy (NE) metric, consolidates process outcomes across heat source settings (power ...
Mahdi Alishavandi, Rahmi Ünal, Metin U. Salamci   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Development of Novel Semi-Stranded Windings for High Speed Electrical Machines Enabled by Additive Manufacturing

, 2023
Recent advances in electrical machines and energy storage technologies make electric vehicles (EVs) feasible replacements to conventional internal combustion engines.
Mohamed N. Ibrahim, Ahmed Selema, Sergeant, Peter, Peter Sergeant, Ibrahim, Mohamed, Selema, Ahmed   +5 more
core   +1 more source

Oxygen uptake, reuse stability, and recycling of copper powder in powder bed fusion

Materials & Design
Oxidation behavior and reuse stability of copper (Cu) powder were systematically investigated for laser- and electron-beam-based powder bed fusion (PBF-LB/M and PBF-EB/M) as a function of process atmosphere and reuse cycles. Repeated powder reuse altered
Robert Ortmann, Arne Röttger, Fabienne Hellwig, Nick Hantke, Tobias Grimm, Eric Schneider, Christian Sternemann, Jan T. Sehrt   +7 more
doaj   +1 more source

A review of hybrid additive manufacturing of metal parts

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2022
This article provides an overview of the latest developments in the field of hybrid additive manufacturing of metal parts. The concept and various kinds of additive manufacturing are discussed.
A. V. Balyakin, M. A. Oleynik, E. P. Zlobin, D. L. Skuratov   +3 more
doaj   +1 more source

Generation of patterned indentations for additive manufacturing technologies

IISE Transactions, 2018
This article proposes a novel approach to generate patterned indentations for different additive manufacturing methodologies.
Ulas Yaman, Melik Dolen, Christoph M. Hoffmann   +2 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Fundamental investigation on the impact of Cu powder oxidation states on processability by powder bed Fusion-Laser Beam/Metal (PBF-LB/M)

Materials & Design
This study introduces targeted oxidation of Cu powders as a strategy to improve both laser power coupling and powder reusability for the PBF-LB/M process.
Arne Röttger, Jonas Hankel, Robert Ortmann, Eric Schneider, Fabienne Hellwig, Milli Suchita Kujur, Tobias Grimm, Christian Sternemann, Jan T. Sehrt   +8 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Finite Element Analysis of the Milling of Ti6Al4V Titanium Alloy Laser Additive Manufacturing Parts

, 2021
This study aimed to analyze the defects of large residual stress in laser additive manufacturing metal parts by establishing a milling numerical simulation of Ti6Al4V titanium alloy thin-walled parts based on the Johnson-Cook constitutive model of ...
Zhuhong Li, Zhen Liu, Zhaohui Ren, Yunhe Wang, Xingwen Zhang   +4 more
core   +1 more source