Results 91 to 100 of about 344,504 (276)
Statistical power for detecting epistasis QTL effects under the F-2 design
Epistasis refers to gene interaction effect involving two or more genes. Statistical methods for mapping quantitative trait loci (QTL) with epistasis effects have become available recently.
Da Yang, Mao Yongcai
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Cassava mosaic disease (CMD) is one of the most devastating Gemini viral diseases that challenge the cassava production with great economic loss. Utilizing host plant resistance through marker assisted breeding is the best sustainable way to tackle this
P. Vidya +4 more
doaj
Mapping of imprinted quantitative trait loci using immortalized F2 populations.
Mapping of imprinted quantitative trait loci (iQTLs) is helpful for understanding the effects of genomic imprinting on complex traits in animals and plants.
Yongxian Wen, Weiren Wu
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
GIS-based multicriteria analysis as decision support in flood risk management [PDF]
In this report we develop a GIS-based multicriteria flood risk assessment and mapping approach. This approach has the ability a) to consider also flood risks which are not measured in monetary terms, b) to show the spatial distribution of these multiple ...
Haase, Dagmar +2 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Additive mappings on symmetric matrices
Let \(F_1\) and \(F_2\) be two fields and let \(S_n(F_1)\) and \(S_n(F_2)\) be the set of symmetric matrices over \(F_1\) and \(F_2\), respectively. A mapping \(\Phi: S_n(F_1)\to S_n(F_2)\) is called additive if \(\Phi(A+B)=\Phi(A)+\Phi(B)\). It is said that \(\Phi\) doesn't increase rank-one if \(rk(\Phi(A))\leq1\) whenever \(rk(A)=1\). \textit{M.
Kuzma, Bojan, Orel, Marko
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

