Results 111 to 120 of about 79,677 (309)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

K-balanced games and capacities [PDF]

open access: yes
In this paper, we present a generalization of the concept of balanced game for finite games. Balanced games are those having a nonempty core, and this core is usually considered as the solution of game.
Michel Grabisch, Pedro Miranda
core  

Beyond prototyping: mapping the relative advantages of adopting additive manufacturing for industrial production [PDF]

open access: yes
Additive Manufacturing (AM) offers significant potential for product and process transformation due to a range of Relative Advantages (RA) it holds over rival Traditional Manufacturing (TM) for low-volume industrial production.
Braziotis, Christos   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Additive Manufacturing of Smart Footwear Components for Healthcare Applications

open access: yes
Diabetic foot complications pose significant health risks, necessitating innovative approaches in orthotic design. This study explores the potential of additive manufacturing in producing functional footwear components with lattice-based structures for ...
Bala Vaidhyanathan   +1 more
core   +1 more source

Deep Learning-Assisted Porosity Assessment for Additive Manufacturing Components Using Ultrasonic Coda Waves

open access: yesSensors
The porosity of additive manufacturing components significantly impacts their mechanical properties, thereby limiting their widespread application in engineering.
Xinyi Yuan, Xianmin Chen, Fang Wen
doaj   +1 more source

Additivity of multiplicative maps on triangular rings

open access: yesLinear Algebra and its Applications, 2011
A bijective map \(\sigma\) between rings is called an \(n\)-isomorphism if it satisfies \((x_1x_2\cdots x_n)^\sigma=x_1^\sigma x_2^\sigma\cdots x_n^\sigma\). Analogously one defines \(n\)-multiplicative derivations and \(n\)-elementary maps. Under certain technical restrictions it is shown that these maps are automatically additive on triangular rings.
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Computational Design and Additive Manufacturing of Conformal Metasurfaces by Combining Topology Optimization With Riemann Mapping Theorem

open access: yes, 2017
In this paper, we present a computational framework for computational design and additive manufacturing of spatial free-form periodic metasurfaces. The proposed scheme rests on the level-set based topology approach and the conformal mapping theory.
Panagiotis Vogiatzis   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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