Results 131 to 140 of about 368,887 (313)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

A Study of Metal-Cement Composites with Additives

open access: yes
The application of small-sized metal fillers (SMF) provides a combination of high bulk density, increased durability and ferromagnetic properties of composite materials on the cement basis.
Tatarinovs, Aleksejs   +3 more
core  

Toxicological evaluation of certain food additives and contaminants / prepared by the Joint FAO/WHO Expert Committee on Food Additives, Rome, 19-28 March 1984

open access: yes, 1984
French ed. "OMS série Additifs alimentaires", only nos. 1-8 publishedNos.
Joint FAO/WHO Expert Committee on Food Additives   +1 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Safety evaluation of certain food additives / prepared by the Seventy-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)

open access: yes, 2012
v, 335 ...
World Health Organization   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Safety evaluation of certain food additives: prepared by the one-hundredth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)

open access: yes
v, 279 p.This publication contains monographs prepared at the one-hundredth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome from 10 to 19 June 2025. It presents the Committee’s evaluation of selected food additives,
World Health Organization   +1 more
core  

Safety evaluation of certain food additives and contaminants / prepared by the fifty-ninth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)

open access: yes, 2003
425 ...
Joint FAO/WHO Expert Committee on Food Additives. Meeting. (59th : 2002: Geneva, Switzerland)
core  

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