Results 141 to 150 of about 368,887 (313)

Additional Aspects

open access: yesDeutsches Ärzteblatt international, 2021
Jennifer, Kranz, Joachim, Steffens
openaire   +3 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Safety evaluation of certain food additives: prepared by the ninety-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)

open access: yes
vii, 293 p.This volume of the WHO Food Additives Series presents the toxicological and dietary exposure evaluations prepared by the ninety-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome in October–November ...
World Health Organization   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Investigation of Wear And Coefficient of Friction in Sliding Friction Pairs Using Oil with Additives

open access: yes
Although oil contains different additives that manufacturer has already added, there are variety of additional chemicals which are meant to improve wear resistance and extend friction pairs life.
Leitāns, Armands   +2 more
core  

Safety evaluation of certain food additives and contaminants./ prepared by the sixty-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JEFCA)

open access: yes, 2007
" ...
Joint FAO/WHO Expert Committee on Food Additives. Meeting (67th : 2006 : Geneva, Switzerland)   +1 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Toxicological evaluation of certain food additives and contaminants / prepared by the 29th meeting of the Joint FAO/WHO Expert Committee on Food Additives, Geneva, 3-12 June 1985

open access: yes, 1987
French ed. "OMS série Additifs alimentaires", only nos. 1-8 publishedPublished on behalf of the World Health OrganizationNos.
World Health Organization   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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