Results 101 to 110 of about 12,996,285 (285)

The Cost of Address Translation

open access: yes, 2012
Modern computers are not random access machines (RAMs). They have a memory hierarchy, multiple cores, and virtual memory. In this paper, we address the computational cost of address translation in virtual memory.
Jurkiewicz, Tomasz, Mehlhorn, Kurt
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

President Bergeron\u27s 98th Commencement Address [PDF]

open access: yes, 2016
President Bergeron offers remarks on A Whole New Way of Listening to the Class of ...
Bergeron, Katherine
core   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A. S. Pushkin’s Address “To a Kalmyk Maiden”: Aspects of Genre Originality

open access: yesOriental Studies, 2018
The main feature of the genre of the poetic form in question is an appeal to the addresses. The article defines the typology of addresses, including addresses to a recipient who is by default unable to response - as in A.S. Pushkin’s Address “To a Kalmyk
B. Kichikova
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

IPv6 Dynamic Address Tunnel Model Based on the Sliding Address Window

open access: yesDianxin kexue, 2015
IPv6 network address hopping transmission technology can effectively prevent network attacks through traffic analysis.On the basis of the study of some related technologies,the concept of dynamic address chain was applied to the IPv6 network address ...
Zichuan Ma   +3 more
doaj   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Factors motivating maternal healthcare clients to use mHealth interventions in rural Malawi.

open access: yesPLOS Digital Health
Client-facing mHealth interventions have the potential to address the inequalities in accessing health information. In maternal healthcare, mHealth interventions provide information to pregnant women on how they can stay healthy during pregnancy, as well
Priscilla Maliwichi   +2 more
doaj   +1 more source

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