Results 81 to 90 of about 83,570 (309)

INSTITUTIONAL DISCOURSE AS THE SPACE OF ADDRESSEE CATEGORY REALIZATION

open access: yesГуманитарные и юридические исследования, 2021
The article studies the status of addressee category as an object of the institutional discourse (ID) on the basis of the principles of modern linguistics. Relevancy of its studying is brought out of a primary thesis about the importance of the component
E. S. Grushevskaya
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

The metaphorical construction of complex domains:the case of speech activity in English. [PDF]

open access: yes, 2005
In this article I provide an account of the way in which the domain of spoken communication is metaphorically constructed in English, on the basis of the analysis of over 450 metaphorical references to speech activity in a corpus of contemporary written ...
Semino, Elena
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Defence of Intentionalism about Demonstratives [PDF]

open access: yes, 2019
Intentionalism about demonstratives is the view that the referent of a demonstrative is determined solely by the speaker's intentions. Intentionalists can disagree about the nature of these intentions, but are united in rejecting the relevance of other ...
Radulescu, Alex
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Annotating honorifics denoting social ranking of referents [PDF]

open access: yes, 2011
This paper proposes an annotating scheme that encodes honorifics (respectful words). Honorifics are used extensively in Japanese, reflecting the social relationship (e.g. social ranks and age) of the referents.
Nakaiwa, Hiromi   +2 more
core   +3 more sources

The Cognitive Metaphor as the Basic of the Social Advertising Creolized Text

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2016
As the main purpose of social advertising is to change the behavioral model of society, the problem of using the linguistic resources for creating a bright memorable image of advertised object is of great practical and theoretical impotance in our time ...
Elena Vladimirovna Yuryeva
doaj   +1 more source

Analysis of prepositions: near and away from Frames of reference. [PDF]

open access: yes, 2017
XXII Jornades de Foment de la Investigació de la Facultat de Ciències Humanes i Socials (Any 2017)Traditional strategies and procedures to learn a foreign language include the study of rules of grammar and doing exercises such as filling ...
Flor Fabregat, Nuria
core   +1 more source

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