Results 81 to 90 of about 1,692 (246)
ЗАСОБИ ВИОКРЕМЛЕННЯ ОБ'ЄКТА У ХУДОЖНЬОМУ ТЕКСТІ [PDF]
, 2018 The article describes the means of identifying a particular object in a literary text. The purpose of the article is to study the linguistic means to identify the object in dialogue and monologue speech. To achieve this aim of the work it is necessary to
Андрейко, Я. В. +1 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Genre System of English Language Restaurant Online Discourse
SHS Web of Conferences, 2018 The article basing on the case study of English-language websites of British restaurants and taking into account such discursive parameters as the goal of communication, content, addresser and addressee factors, communicative strategies, and linguistic ...
Terentyeva Elena +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Expression of relations between the addresser and the addressee in television commercials
, 2010 Lingvistinė pragmatika iš kitų lingvistikos šakų išsiskiria tuo, kad analizuoja tekstui žmonių priskiriamas prasmes, prielaidas, tikslus, veiksmų rūšis (pavyzdžiui, prašymus, skatinimus), kurias jie vykdo kalbėdami.
Dobržinskienė, Rasa
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РОЛЬ АДРЕСАНТА У ВИСЛОВЛЮВАННЯХ ПОХВАЛИ (НА МАТЕРІАЛІ АНГЛОМОВНОГО ХУДОЖНЬОГО ДИСКУРСУ) [PDF]
, 2023 The article is devoted to the investigation of the addresser’s role in expressions of praise. It has been found that praise is a context-bound communicative phenomenon.
Клочко, Лариса Іванівна
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The role of indexical similes in a personal space creation of an addresser
, 2017 Стаття має на меті розкрити індексальну природу художнього порівняння як словесного знаку. У статті надається визначення поняття “індексальне художнє порівняння” і пропонується індексальна класифікація художніх порівнянь з їх поділом на займенникові ...
Просянникова, Я. Н. +2 more
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