Results 101 to 110 of about 4,105,512 (288)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Addressing the Food Aid Curse [PDF]

open access: yes
In this paper, we build a model of agrarian economies in which a kleptocratic government taxes farmers to maximize its life-time utility. The model is a dynamic general equilibrium model in which the subsistence of farmers requires a minimum level of ...
Max Blouin, Stéphane Pallage
core  

Addressing gender norms in Ethiopia’s wheat sector [PDF]

open access: yes, 2019
Poster prepared for a share fair, Addis Ababa, May ...
Badstue, Lone B.
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Soil fungal communities and their impact on ginseng quality under different land use patterns

open access: yesJournal of Agriculture and Food Research
Compared to farmland soil, forest soil is considered the best soil for producing wild simulated ginseng. The main soil factors that cause differences in the quality of ginseng cultivation between forest and farmland soil are not fully understood, and ...
Zhefeng Xu   +10 more
doaj   +1 more source

Teaching with wikis: addressing the digital divide [PDF]

open access: yes, 2008
This paper addresses some aspects of the digital divide affecting teachers and learners in higher education. These relate to divisions arising from variable rates of technology adoption by teachers, which may be especially problematic when students ...
Benson, Robyn   +2 more
core  

Optical addressing of an individual erbium ion in silicon

open access: yes, 2013
The detection of electron spins associated with single defects in solids is a critical operation for a range of quantum information and measurement applications currently under development.
de Boo, Gabriele G.   +6 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Transforming Kenya’s addressing landscape: use case models approach to a responsive National Addressing System

open access: yesFrontiers in Sustainable Cities
The rapid urbanization and population growth in Kenya highlight the need to revive the National Addressing System (NAS). This study aims to examine address systems across the globe, focusing on countries known for their efficient addressing ...
Isaac Kipkemoi, Innocent Osoro Ngare
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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