Results 211 to 220 of about 487,247 (373)

Effects of Adenine-Nucleotides on the Sequence-Specificity of Origin Recognition Complex-Binding to DNA.

open access: bronze, 2002
Hitomi Takenaka   +6 more
openalex   +2 more sources

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Metallothionein‐Inspired Asymmetric Heteroatom Doping of Single‐Atom Nanozymes for Multi‐Enzyme Biocatalysis

open access: yesAdvanced Science, EarlyView.
A metallothionein‐inspired heteroatom doping strategy is reported to construct asymmetric Fe single‐atom catalysts, which display markedly enhanced multi‐enzyme activities—including NADH oxidase‐, oxidase‐, peroxidase‐, and catalase‐like activities. This high multi‐enzyme efficiency arises from atomically dispersed Fe from biomineralization, the large ...
Kaijuan Chen   +6 more
wiley   +1 more source

A Modular Biosensor Platform for the Detection of Plastic Monomers and the Engineering of Promiscuous Amidases Toward Challenging Substrates

open access: yesAdvanced Science, EarlyView.
A luciferase is used as biosensor for aldehydes, produced enzymatically from different monomeric building blocks of plastics like polyurethanes (PUs). The screening platform is used to monitor esterase, amidase, and urethanase activity and to guide the selection of enzyme variants with improved hydrolytic activities toward difficult to hydrolyze ...
Ina Somvilla   +12 more
wiley   +1 more source

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