Results 211 to 220 of about 409,167 (281)

Semiconducting Tungsten Trioxide Thin Films for High-Performance SERS Biosensors. [PDF]

open access: yesNanomaterials (Basel)
Liu H   +6 more
europepmc   +1 more source

Upconversion Nanoparticles‐Based Multimodal Tumor Therapy Integrating Photoclick‐Induced Aggregation of Gold Nanoparticles and Ceria‐Curcumin Redox Modulation With Inflammation Attenuation Post‐Treatment

open access: yesAggregate, EarlyView.
A multifunctional nanoplatform (USiCeCurAu) integrating UCNPs, AuNPs, CeO2, and TK‐CUR‐TPP enables synergistic PDT, CDT, and mPTT. The AuNPs act as pore lockers, UCNPs convert NIR into UV/Vis emission, which triggers AuNPs aggregation, TPP‐CUR‐mediated mitochondria damage for HSP70 suppression, and CeO2‐enabled dual role in ROS generation and ...
Junyou Li   +8 more
wiley   +1 more source

Autofluorescence Imaging and Virtual Histological Staining of Human Prostate Sections for Cancer Diagnosis

open access: yesAdvanced Intelligent Systems, EarlyView.
Autofluorescence imaging with virtual histological staining streamlines postoperative histopathology. Using a deep ultraviolet light‐emitting diode (LED)‐based imaging system and a weakly supervised deep learning model, virtual hematoxylin and eosin (H&E)‐stained images are generated from the autofluorescence of prostate tissue. Pathologist evaluations
Mingxuan Si   +9 more
wiley   +1 more source

Late‐Stage Conversion of Terminal Alkynes to Nitriles in Nucleoside Scaffolds: A Tool for Diversification

open access: yesAsian Journal of Organic Chemistry, EarlyView.
We established a metal‐free, late‐stage diversification of terminal alkynes into nitriles using tert‐butyl nitrite (tBuONO). Replacing 2‐picoline N‐oxide with N‐methylmorpholine N‐oxide (NMO) as the oxidant enabled efficient nitrile formation under mild conditions. Abstract The small nucleoside molecule LJ‐4827 exhibited potent kinase inhibition and in
Yun A Yum   +5 more
wiley   +1 more source

Studies of α′,β′‐Epoxyketone Synthesis by Small‐Molecule Flavins and Flavoenzymes

open access: yesAngewandte Chemie, EarlyView.
A combined synthetic and biochemical approach links the flavoenzyme EpxF to three key steps in epoxomicin biosynthesis. Crystallography, mutagenesis, and 13C‐labeling complete the mechanistic picture of α′,β′‐epoxyketone formation and illustrate the potential of flavin‐mediated transformations.
Alexandra Walter   +5 more
wiley   +2 more sources

DNA base pairs: the effect of the aromatic ring on the strength of the Watson-Crick hydrogen bonding.

open access: yesOrg Biomol Chem
Nieuwland C   +7 more
europepmc   +1 more source

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