Results 211 to 220 of about 393,841 (281)

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Nicotinamide Attenuates Complement and Coagulation Pathways and Resultant Renal Fibrosis. [PDF]

FASEB J
Kin S, Oe Y, Obara T, Sato E, Takahashi N, Miyazaki M, Tanaka T.   +6 more
europepmc   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

High-throughput analyses of a reconstituted diversity-generating retroelement identify intrinsic and extrinsic determinants of diversification. [PDF]

PLoS Genet
Unlu I, Smiley MK, Potapov V, Renoux-Martin Y, Sun ZY, Lim HC.   +5 more
europepmc   +1 more source

Editing and synthetic engineering of chloroplast genomes. [PDF]

Plant Commun
Fu J, Zhang J.
europepmc   +1 more source

Role of Calpains in Uremia-Related Functional and Structural Muscle Changes: Protective Effect of Calpastatin Overexpression. [PDF]

Cells
Gutiérrez-Calabrés E, Campillo S, Alcalde-Estévez E, Cuevas-Delgado P, Barbas C, García-Villoria S, Silvestre-Vargas A, Griera M, de Frutos S, Ruiz-Torres MP, Rodríguez-Puyol D, Calleros L.   +11 more
europepmc   +1 more source

Site-specific ribozyme-mediated alkylation of DNA substrates. [PDF]

Nucleic Acids Res
He Y, Wilson TJ, Deng J, Luo Y, Yan K, Xie Y, Lilley DMJ, Huang L.   +7 more
europepmc   +1 more source

Epigenome analysis of an algae-infecting giant virus reveals a unique methylation motif catalogue. [PDF]

PLoS One
Truchon AR, Zinser ER, Wilhelm SW.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Correction: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells. [PDF]

Cell Mol Life Sci
Rose I, Greenwood M, Biggart M, Baumlin N, Tarran R, Hart SL, Baines DL.   +6 more
europepmc   +1 more source