Results 201 to 210 of about 252,905 (308)

<i>Lactiplantibacillus plantarum</i> HY7718 Modulates Gut-Kidney Axis-Associated Inflammation, Gastrointestinal Dysfunction, and Gut Microbiota in Adenine-Induced Chronic Kidney Disease Mice. [PDF]

Int J Mol Sci
Kim H, Jeong JW, Kim JY, Shim JJ, Lee JH.   +4 more
europepmc   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

Host-derived nitrate fuels indole production by <i>Escherichia coli</i> to drive chronic kidney disease progression. [PDF]

Science
Lee JY, Mahan SP, Parente de Carvalho T, Nguyen H, Singai C, Camacho L, Tekeli M, Kwon YJ, Lee JW, Santos RL, Tsolis RM, Winter SE, Bäumler AJ.   +12 more
europepmc   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

RETRACTED: Huang et al. Adenine Inhibits the Invasive Potential of DLD-1 Human Colorectal Cancer Cell via the AMPK/FAK Axis. <i>Pharmaceuticals</i> 2021, <i>14</i>, 860. [PDF]

Pharmaceuticals (Basel)
Huang CW, Lin YC, Hung CH, Chen HM, Lin JT, Wang CJ, Kao SH.   +6 more
europepmc   +1 more source

An Electrophilic Uridine Building Block for Post‐Synthetic RNA Modification as Exemplified for Spin Labeling

Chemistry – A European Journal, EarlyView.
An electrophilic 5‐isothiocyanatomethyl uridine building block enables modular post‐synthetic RNA labeling with primary amine‐containing probes. Positioning the functionality in the major groove minimizes structural perturbation and allows facile conjugation of sensitive tags such as TEMPO spin labels for paramagnetic relaxation enhancement studies ...
Lisa Ruetz, Sonja Leiner, Alessandro Marotto, Raphael Plangger, Christoph Kreutz   +4 more
wiley   +1 more source

Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review). [PDF]

Int J Mol Med
Figueroa SM, Huang S, Reyes-Osorio J, Boffa JJ, Amador CA, Chadjichristos CE, Boutin L.   +6 more
europepmc   +1 more source

Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure

Chemistry – A European Journal, EarlyView.
The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio, Marko Trajkovski, Janez Plavec, Claudia Sissi   +3 more
wiley   +1 more source

Tubular Omega-3 Fatty Acid Receptor FFAR4 Deficiency Aggravated Renal Aging and Chronic Kidney Disease. [PDF]

Aging Cell
Yang L, Tang L, Li J, Liu D, Hu C, Guo F, Lin L, Huang R, Fu P, Ma L.   +9 more
europepmc   +1 more source

Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion

Chemistry – A European Journal, EarlyView.
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang, Nemanja Djokovic, Alexander Herr, Anna Wacker, Emily Swanson Hay, Daniel Santana, Amanda E. Hargrove, Harald Schwalbe, Katarina Nikolic, Frank Abendroth, Olalla Vázquez   +10 more
wiley   +1 more source