Results 271 to 280 of about 401,272 (328)

Identification and structural insights into RNA motifs targeted by a CAG repeat DNA-binding small molecule. [PDF]

Chem Sci
Chen Q, Fujiwara A, Nakatani K, Kawai G, Murata A.   +4 more
europepmc   +1 more source

Selective Oxidation of α,β‐Unsaturated Alcohols With Lyophilisates of Bjerkandera adusta

Chemistry &Biodiversity, EarlyView.
ABSTRACT The biocatalytic aerobic production of (E)‐2‐allylic aldehydes from their corresponding alcohols using lyophilisates of the basidiomycetous fungus Bjerkandera adusta is reported. The addition of small amounts of organic solvents to the reaction media increased the reaction and substrate conversion rates, allowing for to produce (E)‐aldehydes ...
Letizia Calza, Valeriia Nikitenkova, Wendell Albuquerque, Holger Zorn, Tatyana Zhuk   +4 more
wiley   +1 more source

Genome-scale metabolic modelling of trimethoprim’s mode of action reveals free ATP salvaged to restore purine pool

Carter C, Singh D, Wain J, Langridge GC.
europepmc   +1 more source

Dual Role of Exosomes in Parkinson's Disease: Adenine Exerts a Beneficial Effect. [PDF]

CNS Neurosci Ther
Chen L, Shao YT, Geng J, Liu H, Liu QS, Cheng Y, Sun T.   +6 more
europepmc   +1 more source

Fungal Biodiversity From the Atlantic Forest With Bioactive Metabolites Against Cutaneous Leishmaniasis

Chemistry &Biodiversity, EarlyView.
ABSTRACT Biodiversity offers a rich source of bioactive compounds for drug discovery. We isolated Aspergillus fumigatus from compost in the Atlantic Forest and found its extract active against Leishmania (Leishmania) amazonensis. Two crude extracts, I06 and I75, were selected for further study.
Juliana Cristina Pereira Calado, Marina Valente Navarro, Alison Felipe Alencar Chaves, Isis Casula, Patricia Locosque Ramos, João Batista da Cruz, Anderson Messias Rodrigues, Keith Dayane Leite Lira, Fernando Luiz Affonso Fonseca, Patricia Xander, Suzan Pantaroto de Vasconcellos, Wagner Luiz Batista   +11 more
wiley   +1 more source

Characterisation of Ventricular Nucleotide Metabolism and Clinical Predictors Associated with the Onset of Atrial Fibrillation Following Cardiac Surgery. [PDF]

J Clin Med
Fudulu DP, Dimagli A, Moscarelli M, Kota R, Dong T, Gemelli M, Sandhu M, Suleiman S, Angelini GD.   +8 more
europepmc   +1 more source

A Thermostable Fatty Acid Hydratase from Marinitoga Piezophila with Low Temperature Optimum and Broad Product Scope

ChemBioChem, EarlyView.
A rare thermostable Fatty Acid Hydratase ortholog from Marinitoga Piezophila, a thermo‐piezophilic organism, displays novel properties. While the enzyme has excellent thermostability (retaining full activity after incubation at 70°C), quite interestingly, it shows the highest activity at 20 °C. Moreover the enzyme has a broad substrate scope and unique
Niels Krabbe Johnsen, David Marlo Werenberg Marcher, Mathias Bille Nielsen, Yan Zhang, Zheng Guo, Bekir Engin Eser   +5 more
wiley   +1 more source

Effect of histidine and carnosine on haemoglobin recovery in anaemia induced-kidney damage and iron-loading mouse models. [PDF]

Amino Acids
Vera-Aviles M, Moreno-Fernandez J, Kose T, Hider R, Latunde-Dada GO.   +4 more
europepmc   +1 more source

Revisiting the Reaction Mechanism of Electrochemical 1,4‐NADH Regeneration on Carbon Electrodes

ChemCatChem, EarlyView.
The mechanism of NAD+ electrochemical reduction on carbon‐based electrodes varies with the applied potential. Catalyst loading, buffer, and initial NAD+ concentration can be optimized to achieve the highest 1,4‐NADH selectivity. Abstract The direct electrochemical regeneration of 1,4‐NADH, an essential cofactor in many enzymatic reactions, has emerged ...
Mohammed Ali Saif Al‐Shaibani, Saksham Verma, Luka A. Zivkovic, Tanja Vidakovic‐Koch   +3 more
wiley   +1 more source

The Electronic Properties of Cordycepin in the Adenine Nucleoside Landscape: A Theoretical Approach. [PDF]

Molecules
Karwowski BT.
europepmc   +1 more source