Results 91 to 100 of about 370,851 (253)

Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium

, 1975
The translocation of adenine nucleotides across the inner mitochondrial membrane and the tissue concentration of long-chain acyl-CoA esters were studied in dog heart after experimental myocardial ischemia.
AL Shug, null Koke, JD Folts, N Bittar, E Shrago   +4 more
core   +1 more source

The influence of circadian variables on ecotoxicology metabolomics

Biological Reviews, EarlyView.
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester, David J. Beale, Anthony R. Carroll, Steven D. Melvin   +3 more
wiley   +1 more source

Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain

Nature Communications, 2020
Trypanosoma brucei guanosine 5′-monophosphate reductase (TbGMPR) catalyses the conversion of GMP to inosine 5′-monophosphate and contains a cystathionine-β-synthase (CBS) domain. Here the authors combine X-ray crystallography and kinetic measurements and
Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi, Manatsu Tamura, Bruno Kilunga Kubata, Katsuaki Inoue, Robert P. Rambo, Susumu Uchiyama, Kentaro Ishii, Shigenori Nishimura, Takashi Inui   +12 more
doaj   +1 more source

Effects of high glucose on adenine nucleotides.

, 2015
Data are means ± SEM (n = 4–5/group). Nucleotide values are expressed as nmol/mg muscle.Effects of high glucose on adenine nucleotides.
Gregory J. Cooney (183923), Edward W. Kraegen (183918), Vera Schultz (743022), Rudy J. Valentine (743020), Asish K. Saha (743024), Kimberly A. Coughlan (743018), Amanda Brandon (743023), Robert Petrocelli (743021), Neil B. Ruderman (172181), Thomas W. Balon (743019)   +9 more
core   +1 more source

Role of adenine nucleotide translocator 1 in mtDNA maintenance

, 2000
Autosomal dominant progressive external ophthalmoplegia is a rare human disease that shows a Mendelian inheritance pattern, but is characterized by large-scale mitochondrial DNA (mtDNA) deletions. We have identified two heterozygous missense mutations in
Tiranti V., Zeviani M., Keranen S., Suomalainen A., Kaukonen J., Comi G. P., Kyttala A., Juselius J. K., Peltonen L., Suomalainen, Anu, Juselius, Jukka, Tiranti, Valeria, Comi, Giacomo, Kyttälä, Aija, Peltonen, Leena, Zeviani, Massimo, Kaukonen, Jyrki, Keränen, Sirkka   +17 more
core   +2 more sources

Formation of Lanthanide Luminescent Aggregates With RNA Using Tripodal Europium [Eu(III)] BTA Self‐Assembled Complexes

Chemistry – A European Journal, EarlyView.
The two Eu(III) complexes of 1.Eu and 2.Eu, that were formed in situ, were used to bind to yeast RNA and A10 (RNA) in a buffered pH 7 solution. The interaction gave rise to changes in the lanthanide‐centered emission because of direct binding of these complexes, which resulted in aggregation of the RNA, as demonstrated using phase‐contrast and atomic ...
Tómas A. Gudmundsson, Changzhuang Bai, Grace E. Maynard, Pall Thordarson, Thorfinnur Gunnlaugsson   +4 more
wiley   +1 more source

The crystal structure of human ferroptosis suppressive protein 1 in complex with flavin adenine dinucleotide and nicotinamide adenine nucleotide

MedComm
Ferroptosis is a recently discovered form of regulated cell death characterized by its distinct dependence on iron and the peroxidation of lipids within cellular membranes. Ferroptosis plays a crucial role in physiological and pathological situations and
Shijian Feng, Xiaofang Huang, Dan Tang, Xiaoyu Liu, Liang Ouyang, Dehua Yang, Kunjie Wang, Banghua Liao, Shiqian Qi   +8 more
doaj   +1 more source

Serum and Striatal Redox and Metabolic Responses to Progesterone Treatment in Rats with Common Carotid Ligation

Antioxidants
Cerebrovascular and neurodegenerative diseases are often linked to dysregulated cerebral blood flow, which results in oxidative stress and alterations in energy metabolism.
Ivana Guševac Stojanović, Ana Todorović, Filip Veljković, Katarina Bobić, Jelena Martinović, Snežana Pejić, Suzana Veličković, Zoran Stojanović, Dunja Drakulić   +8 more
doaj   +1 more source

Brain injury alters ectonucleotidase activities and adenine nucleotide levels in rat serum [PDF]

Journal of Medical Biochemistry, 2015
Background: Cortical stab injury (CSI) induces changes in the activity, expression and cellular distribution of specific ectonucleotidases at the injury site.
Laketa Danijela, Savić Jasmina, Bjelobaba Ivana, Lavrnja Irena, Vasić Vesna, Stojiljković Mirjana, Nedeljković Nadežda   +6 more
doaj  

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source